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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STAT5B All Species: 27.88
Human Site: Y33 Identified Species: 61.33
UniProt: P51692 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51692 NP_036580.2 787 89866 Y33 F P I E V R H Y L S Q W I E S
Chimpanzee Pan troglodytes XP_511502 782 89188 Y33 F P I E V R H Y L S Q W I E S
Rhesus Macaque Macaca mulatta XP_001109557 794 90645 Y33 F P I E V R H Y L A Q W I E S
Dog Lupus familis XP_548092 787 90122 Y33 F P I E V R H Y L S Q W I E S
Cat Felis silvestris
Mouse Mus musculus P42232 786 89984 Y33 F P I E V R H Y L S Q W I E S
Rat Rattus norvegicus P52632 786 90205 Y33 F P I E V R H Y L S Q W I E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q6DV79 771 88152 F33 F P M E L R Q F L A P W I E S
Frog Xenopus laevis Q7ZXK3 766 87581 F33 F P M E L R Q F L A P W I E S
Zebra Danio Brachydanio rerio NP_919368 785 89465 Y33 F P I E V R H Y L S Q W I E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24151 761 86396 C32 G M L E L R L C L A P W I E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAD6 706 80563 T19 A L T D V S K T C H H L W E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 92.6 97 N.A. 96.8 96.8 N.A. N.A. 28.4 29.4 79 N.A. 31.2 N.A. 23.1 N.A.
Protein Similarity: 100 95.6 95 98.5 N.A. 98.2 98.3 N.A. N.A. 49.2 49.2 88.4 N.A. 49.5 N.A. 42.6 N.A.
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. N.A. 60 60 93.3 N.A. 40 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 86.6 86.6 93.3 N.A. 60 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 37 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 91 0 0 0 0 0 0 0 0 0 100 10 % E
% Phe: 82 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 64 0 0 10 10 0 0 0 0 % H
% Ile: 0 0 64 0 0 0 0 0 0 0 0 0 91 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 0 28 0 10 0 91 0 0 10 0 0 0 % L
% Met: 0 10 19 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 82 0 0 0 0 0 0 0 0 28 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 19 0 0 0 64 0 0 0 0 % Q
% Arg: 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 0 0 0 55 0 0 0 0 73 % S
% Thr: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 73 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 91 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _