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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN2
All Species:
5.45
Human Site:
S743
Identified Species:
12
UniProt:
P51788
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51788
NP_004357.3
898
98535
S743
A
A
S
E
K
L
E
S
C
E
K
R
K
L
K
Chimpanzee
Pan troglodytes
XP_527935
988
108838
F768
A
G
Q
R
P
S
I
F
Q
S
L
L
H
C
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545230
891
98238
S734
A
A
S
E
L
E
K
S
E
S
C
E
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0A1
908
99419
S751
A
T
S
E
L
E
K
S
E
S
C
D
K
R
K
Rat
Rattus norvegicus
P35525
907
99310
K749
S
T
T
S
E
L
E
K
S
E
S
C
D
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
E715
L
P
G
Q
G
H
R
E
S
F
A
Y
V
D
E
Chicken
Gallus gallus
XP_425521
996
111070
C776
Q
L
F
Q
Q
L
L
C
P
Y
S
R
R
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920936
1562
174909
Q721
R
K
Q
P
R
K
Q
Q
R
K
Q
P
R
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
P823
G
H
S
P
S
I
T
P
Y
T
T
I
T
G
N
Honey Bee
Apis mellifera
XP_392015
919
102193
A718
S
P
L
V
S
P
A
A
T
P
Y
T
T
V
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175776
603
66900
T453
A
A
L
S
G
S
V
T
H
T
I
S
T
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
94.6
N.A.
93.2
93.5
N.A.
48.3
49.2
N.A.
43.1
N.A.
38.8
47
N.A.
40.9
Protein Similarity:
100
62.9
N.A.
96.2
N.A.
95.3
95.5
N.A.
62.9
64.6
N.A.
49.8
N.A.
53.1
62.7
N.A.
54
P-Site Identity:
100
6.6
N.A.
46.6
N.A.
40
20
N.A.
0
13.3
N.A.
0
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
6.6
N.A.
53.3
N.A.
46.6
46.6
N.A.
13.3
40
N.A.
40
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
28
0
0
0
0
10
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
19
10
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
10
10
0
% D
% Glu:
0
0
0
28
10
19
19
10
19
19
0
10
0
0
19
% E
% Phe:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
10
10
10
0
19
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
10
0
0
0
10
0
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
10
10
0
0
0
% I
% Lys:
0
10
0
0
10
10
19
10
0
10
10
0
28
19
28
% K
% Leu:
10
10
19
0
19
28
10
0
0
0
10
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
19
0
19
10
10
0
10
10
10
0
10
0
10
0
% P
% Gln:
10
0
19
19
10
0
10
10
10
0
10
0
0
0
10
% Q
% Arg:
10
0
0
10
10
0
10
0
10
0
0
19
19
19
10
% R
% Ser:
19
0
37
19
19
19
0
28
19
28
19
10
0
10
0
% S
% Thr:
0
19
10
0
0
0
10
10
10
19
10
10
28
0
10
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
10
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _