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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN2
All Species:
1.52
Human Site:
S758
Identified Species:
3.33
UniProt:
P51788
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51788
NP_004357.3
898
98535
S758
R
V
R
I
S
L
A
S
D
A
D
L
E
G
E
Chimpanzee
Pan troglodytes
XP_527935
988
108838
K783
L
G
R
A
R
P
T
K
K
K
T
T
Q
D
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545230
891
98238
L749
L
K
R
V
R
I
S
L
A
S
D
S
D
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0A1
908
99419
L766
L
K
R
V
R
I
S
L
A
S
D
S
D
P
E
Rat
Rattus norvegicus
P35525
907
99310
S764
K
L
K
R
V
R
I
S
L
A
S
D
S
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
G730
E
E
D
E
E
G
S
G
R
T
E
P
P
P
T
Chicken
Gallus gallus
XP_425521
996
111070
P791
T
Q
S
A
V
Q
E
P
V
E
V
I
E
T
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920936
1562
174909
K736
Q
R
K
P
S
N
A
K
L
Y
H
N
G
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
A838
S
E
F
R
I
R
S
A
F
E
A
I
F
K
K
Honey Bee
Apis mellifera
XP_392015
919
102193
L733
G
A
E
S
R
I
R
L
A
F
E
A
I
F
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175776
603
66900
Q468
I
V
F
E
L
T
G
Q
I
T
H
I
L
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
94.6
N.A.
93.2
93.5
N.A.
48.3
49.2
N.A.
43.1
N.A.
38.8
47
N.A.
40.9
Protein Similarity:
100
62.9
N.A.
96.2
N.A.
95.3
95.5
N.A.
62.9
64.6
N.A.
49.8
N.A.
53.1
62.7
N.A.
54
P-Site Identity:
100
6.6
N.A.
20
N.A.
20
13.3
N.A.
0
6.6
N.A.
13.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
13.3
N.A.
53.3
N.A.
53.3
33.3
N.A.
13.3
13.3
N.A.
26.6
N.A.
26.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
19
0
0
19
10
28
19
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
10
0
28
10
19
19
0
% D
% Glu:
10
19
10
19
10
0
10
0
0
19
19
0
19
0
28
% E
% Phe:
0
0
19
0
0
0
0
0
10
10
0
0
10
10
0
% F
% Gly:
10
10
0
0
0
10
10
10
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% H
% Ile:
10
0
0
10
10
28
10
0
10
0
0
28
10
0
0
% I
% Lys:
10
19
19
0
0
0
0
19
10
10
0
0
0
10
10
% K
% Leu:
28
10
0
0
10
10
0
28
19
0
0
10
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
10
0
0
0
10
10
28
0
% P
% Gln:
10
10
0
0
0
10
0
10
0
0
0
0
10
0
0
% Q
% Arg:
10
10
37
19
37
19
10
0
10
0
0
0
0
0
19
% R
% Ser:
10
0
10
10
19
0
37
19
0
19
10
19
10
0
10
% S
% Thr:
10
0
0
0
0
10
10
0
0
19
10
10
0
19
10
% T
% Val:
0
19
0
19
19
0
0
0
10
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _