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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN2
All Species:
14.55
Human Site:
T491
Identified Species:
32
UniProt:
P51788
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51788
NP_004357.3
898
98535
T491
G
I
H
T
D
S
S
T
Y
R
I
V
P
G
G
Chimpanzee
Pan troglodytes
XP_527935
988
108838
I516
G
I
L
F
D
D
I
I
Y
K
I
L
P
G
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545230
891
98238
T482
G
I
H
T
D
S
S
T
Y
R
I
V
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0A1
908
99419
T499
G
I
H
T
D
S
S
T
Y
R
I
V
P
G
G
Rat
Rattus norvegicus
P35525
907
99310
T497
G
I
H
T
D
S
S
T
Y
R
I
V
P
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
V466
W
I
H
P
H
V
S
V
P
I
V
I
F
L
F
Chicken
Gallus gallus
XP_425521
996
111070
V524
G
I
L
F
D
G
I
V
Y
K
I
L
P
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920936
1562
174909
V470
G
I
H
A
D
S
T
V
Y
P
I
V
P
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
L570
G
V
R
Y
G
G
R
L
S
P
I
M
P
G
G
Honey Bee
Apis mellifera
XP_392015
919
102193
I465
G
V
R
Y
G
G
I
I
T
P
I
V
P
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175776
603
66900
T211
V
L
F
S
I
E
V
T
S
V
Y
F
A
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
94.6
N.A.
93.2
93.5
N.A.
48.3
49.2
N.A.
43.1
N.A.
38.8
47
N.A.
40.9
Protein Similarity:
100
62.9
N.A.
96.2
N.A.
95.3
95.5
N.A.
62.9
64.6
N.A.
49.8
N.A.
53.1
62.7
N.A.
54
P-Site Identity:
100
53.3
N.A.
100
N.A.
100
100
N.A.
20
53.3
N.A.
73.3
N.A.
33.3
40
N.A.
6.6
P-Site Similarity:
100
66.6
N.A.
100
N.A.
100
100
N.A.
33.3
66.6
N.A.
80
N.A.
46.6
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
64
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
19
0
0
0
0
0
0
0
10
10
0
10
% F
% Gly:
82
0
0
0
19
28
0
0
0
0
0
0
0
82
82
% G
% His:
0
0
55
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
0
0
10
0
28
19
0
10
82
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% K
% Leu:
0
10
19
0
0
0
0
10
0
0
0
19
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
10
28
0
0
82
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
0
0
10
0
0
37
0
0
0
0
10
% R
% Ser:
0
0
0
10
0
46
46
0
19
0
0
0
0
0
0
% S
% Thr:
0
0
0
37
0
0
10
46
10
0
0
0
0
0
0
% T
% Val:
10
19
0
0
0
10
10
28
0
10
10
55
0
10
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
19
0
0
0
0
64
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _