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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN2
All Species:
30.61
Human Site:
Y230
Identified Species:
67.33
UniProt:
P51788
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51788
NP_004357.3
898
98535
Y230
L
S
L
F
G
G
I
Y
E
N
E
S
R
N
T
Chimpanzee
Pan troglodytes
XP_527935
988
108838
Y257
M
S
V
F
C
G
V
Y
E
Q
P
Y
Y
Y
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545230
891
98238
Y221
L
S
L
F
G
G
I
Y
E
N
E
S
R
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0A1
908
99419
Y238
L
S
L
F
G
G
I
Y
E
H
E
S
R
N
T
Rat
Rattus norvegicus
P35525
907
99310
Y236
L
S
L
F
G
G
I
Y
E
N
E
S
R
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
V218
Y
L
T
L
K
A
F
V
A
K
V
I
A
L
T
Chicken
Gallus gallus
XP_425521
996
111070
Y265
M
S
I
F
C
G
V
Y
E
Q
P
Y
Y
Y
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920936
1562
174909
Y208
M
A
L
F
G
G
I
Y
M
N
E
L
R
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
Y311
V
T
S
F
Q
G
I
Y
E
N
E
S
R
N
S
Honey Bee
Apis mellifera
XP_392015
919
102193
Y206
V
T
S
F
Q
G
I
Y
E
N
E
S
R
N
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175776
603
66900
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
94.6
N.A.
93.2
93.5
N.A.
48.3
49.2
N.A.
43.1
N.A.
38.8
47
N.A.
40.9
Protein Similarity:
100
62.9
N.A.
96.2
N.A.
95.3
95.5
N.A.
62.9
64.6
N.A.
49.8
N.A.
53.1
62.7
N.A.
54
P-Site Identity:
100
33.3
N.A.
100
N.A.
93.3
100
N.A.
6.6
40
N.A.
73.3
N.A.
66.6
66.6
N.A.
0
P-Site Similarity:
100
60
N.A.
100
N.A.
100
100
N.A.
6.6
60
N.A.
86.6
N.A.
86.6
80
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
73
0
64
0
0
0
0
% E
% Phe:
0
0
0
82
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
46
82
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
64
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
37
10
46
10
0
0
0
0
0
0
0
10
0
10
0
% L
% Met:
28
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
55
0
0
0
64
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% P
% Gln:
0
0
0
0
19
0
0
0
0
19
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% R
% Ser:
0
55
19
0
0
0
0
0
0
0
0
55
0
0
19
% S
% Thr:
0
19
10
0
0
0
0
0
0
0
0
0
0
0
64
% T
% Val:
19
0
10
0
0
0
19
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
82
0
0
0
19
19
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _