KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN2
All Species:
34.55
Human Site:
Y553
Identified Species:
76
UniProt:
P51788
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51788
NP_004357.3
898
98535
Y553
Q
S
L
Q
P
S
L
Y
D
S
I
I
R
I
K
Chimpanzee
Pan troglodytes
XP_527935
988
108838
Y578
Q
S
L
Q
P
S
L
Y
D
S
I
I
Q
V
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545230
891
98238
Y544
Q
S
L
Q
P
S
L
Y
D
S
I
I
R
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0A1
908
99419
Y561
Q
S
L
Q
P
S
L
Y
D
S
I
I
R
I
K
Rat
Rattus norvegicus
P35525
907
99310
Y559
Q
S
L
Q
P
S
L
Y
D
S
I
I
R
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
L521
V
L
F
P
D
G
I
L
F
D
G
I
V
Y
K
Chicken
Gallus gallus
XP_425521
996
111070
Y586
Q
S
L
Q
P
S
L
Y
D
S
I
I
Q
V
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920936
1562
174909
Y532
Q
S
L
Q
P
S
L
Y
D
S
I
I
R
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
Y632
A
L
L
Q
P
S
I
Y
D
S
I
I
L
I
K
Honey Bee
Apis mellifera
XP_392015
919
102193
Y527
A
L
L
Q
P
S
I
Y
D
S
I
I
L
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175776
603
66900
L266
F
P
F
D
V
Q
E
L
V
A
F
A
F
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
94.6
N.A.
93.2
93.5
N.A.
48.3
49.2
N.A.
43.1
N.A.
38.8
47
N.A.
40.9
Protein Similarity:
100
62.9
N.A.
96.2
N.A.
95.3
95.5
N.A.
62.9
64.6
N.A.
49.8
N.A.
53.1
62.7
N.A.
54
P-Site Identity:
100
86.6
N.A.
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
93.3
N.A.
73.3
73.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
100
N.A.
100
N.A.
80
80
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
0
82
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
19
0
0
0
0
0
10
0
10
0
10
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
28
0
0
0
82
91
0
73
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% K
% Leu:
0
28
82
0
0
0
64
19
0
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
10
82
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
64
0
0
82
0
10
0
0
0
0
0
0
19
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
46
0
0
% R
% Ser:
0
64
0
0
0
82
0
0
0
82
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
10
0
0
0
10
0
0
0
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _