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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN2
All Species:
16.06
Human Site:
Y64
Identified Species:
35.33
UniProt:
P51788
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51788
NP_004357.3
898
98535
Y64
A
A
P
E
L
L
E
Y
G
R
S
R
C
A
R
Chimpanzee
Pan troglodytes
XP_527935
988
108838
K91
S
S
S
T
V
D
S
K
D
E
D
H
Y
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545230
891
98238
Y55
A
P
P
E
L
L
E
Y
G
Q
S
R
C
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0A1
908
99419
Y72
A
T
P
E
L
L
E
Y
G
Q
S
R
C
A
R
Rat
Rattus norvegicus
P35525
907
99310
Y70
A
T
P
E
L
L
E
Y
G
Q
S
R
C
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
R55
P
R
G
D
A
G
S
R
P
N
V
H
P
T
Q
Chicken
Gallus gallus
XP_425521
996
111070
I99
K
R
E
S
Q
V
E
I
K
E
E
R
Y
S
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920936
1562
174909
Y42
Q
A
P
E
L
L
E
Y
E
K
D
P
C
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
L145
D
K
Q
R
N
K
E
L
L
G
K
H
S
T
R
Honey Bee
Apis mellifera
XP_392015
919
102193
R40
E
E
D
L
R
K
S
R
R
G
P
L
C
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175776
603
66900
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49
N.A.
94.6
N.A.
93.2
93.5
N.A.
48.3
49.2
N.A.
43.1
N.A.
38.8
47
N.A.
40.9
Protein Similarity:
100
62.9
N.A.
96.2
N.A.
95.3
95.5
N.A.
62.9
64.6
N.A.
49.8
N.A.
53.1
62.7
N.A.
54
P-Site Identity:
100
0
N.A.
86.6
N.A.
86.6
86.6
N.A.
0
13.3
N.A.
60
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
33.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
13.3
33.3
N.A.
73.3
N.A.
13.3
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
19
0
0
10
0
0
0
0
0
0
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% C
% Asp:
10
0
10
10
0
10
0
0
10
0
19
0
0
0
0
% D
% Glu:
10
10
10
46
0
0
64
0
10
19
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
0
0
37
19
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
0
19
0
10
10
10
10
0
0
0
37
% K
% Leu:
0
0
0
10
46
46
0
10
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
10
46
0
0
0
0
0
10
0
10
10
10
0
0
% P
% Gln:
10
0
10
0
10
0
0
0
0
28
0
0
0
0
10
% Q
% Arg:
0
19
0
10
10
0
0
19
10
10
0
46
0
10
46
% R
% Ser:
10
10
10
10
0
0
28
0
0
0
37
0
10
19
0
% S
% Thr:
0
19
0
10
0
0
0
0
0
0
0
0
0
19
0
% T
% Val:
0
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _