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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN3
All Species:
22.42
Human Site:
T180
Identified Species:
49.33
UniProt:
P51790
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51790
NP_001820.2
818
90966
T180
C
W
G
S
N
E
T
T
F
E
E
R
D
K
C
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
E175
E
L
I
I
G
Q
A
E
G
P
G
S
Y
I
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848379
760
84902
F165
L
W
A
L
L
F
A
F
L
A
V
S
L
V
R
Cat
Felis silvestris
Mouse
Mus musculus
P51791
818
90851
T180
C
W
G
S
N
E
T
T
F
E
E
R
D
K
C
Rat
Rattus norvegicus
P51792
818
90837
T180
C
W
G
S
N
E
T
T
F
E
E
R
D
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506627
818
90891
T180
C
W
G
S
N
E
T
T
F
E
E
R
D
K
C
Chicken
Gallus gallus
XP_420400
866
96559
T180
C
W
G
S
N
E
T
T
F
E
E
R
D
K
C
Frog
Xenopus laevis
NP_001083736
791
88122
E175
D
L
I
I
G
Q
A
E
G
P
G
S
Y
I
M
Zebra Danio
Brachydanio rerio
XP_001923503
874
97004
T184
C
W
G
S
N
K
T
T
F
A
E
R
D
K
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
A188
G
S
V
G
G
G
L
A
L
G
K
E
G
P
L
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
L175
F
A
L
I
S
T
L
L
V
K
Y
V
A
P
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
N.A.
72.8
N.A.
99.5
99.3
N.A.
98.6
91.8
89
82.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.9
N.A.
83.1
N.A.
99.7
99.7
N.A.
99.3
93.4
92.5
88.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
6.6
N.A.
100
100
N.A.
100
100
0
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
N.A.
6.6
N.A.
100
100
N.A.
100
100
6.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.3
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
50.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
28
10
0
19
0
0
10
0
0
% A
% Cys:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
55
0
0
% D
% Glu:
10
0
0
0
0
46
0
19
0
46
55
10
0
0
0
% E
% Phe:
10
0
0
0
0
10
0
10
55
0
0
0
0
0
0
% F
% Gly:
10
0
55
10
28
10
0
0
19
10
19
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
28
0
0
0
0
0
0
0
0
0
19
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
10
10
0
0
55
0
% K
% Leu:
10
19
10
10
10
0
19
10
19
0
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
28
% M
% Asn:
0
0
0
0
55
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
19
0
0
0
19
0
% P
% Gln:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
10
% R
% Ser:
0
10
0
55
10
0
0
0
0
0
0
28
0
0
0
% S
% Thr:
0
0
0
0
0
10
55
55
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
10
0
10
10
0
10
0
% V
% Trp:
0
64
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _