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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN4
All Species:
13.64
Human Site:
S399
Identified Species:
27.27
UniProt:
P51793
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51793
NP_001821.2
760
84917
S399
Q
S
T
S
E
L
I
S
E
L
F
N
D
C
G
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
K430
L
N
T
S
E
L
I
K
E
L
F
T
D
C
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848379
760
84902
S399
R
S
T
S
E
L
I
S
E
L
F
N
D
C
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61418
747
83956
N390
E
L
I
S
E
L
F
N
D
C
G
A
L
E
S
Rat
Rattus norvegicus
P51794
747
83683
N390
E
L
I
S
E
L
F
N
D
C
G
A
L
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515028
869
97095
S508
Q
S
T
S
E
L
I
S
E
L
F
N
D
C
G
Chicken
Gallus gallus
XP_425575
680
76203
I349
M
T
R
P
V
D
D
I
P
D
R
P
A
G
P
Frog
Xenopus laevis
Q9W701
689
76782
L358
S
R
L
T
M
K
E
L
L
T
S
L
F
D
N
Zebra Danio
Brachydanio rerio
NP_001070786
768
85452
S408
R
S
T
S
E
L
I
S
E
L
F
N
D
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
A469
L
G
T
G
Q
F
L
A
G
E
L
S
T
H
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
G395
P
E
S
V
P
D
S
G
I
E
C
P
R
P
P
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
G406
L
D
M
T
E
S
M
G
I
L
F
H
E
C
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.2
N.A.
99.2
N.A.
96.3
97.3
N.A.
85
82.8
25.3
89
N.A.
20.2
N.A.
N.A.
N.A.
Protein Similarity:
100
85.5
N.A.
100
N.A.
97.5
98.1
N.A.
86.6
85.5
44.6
94.2
N.A.
34.4
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
N.A.
93.3
N.A.
20
20
N.A.
100
0
0
93.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
N.A.
100
N.A.
40
40
N.A.
100
6.6
6.6
100
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.6
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.9
52.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
17
9
0
0
50
0
% C
% Asp:
0
9
0
0
0
17
9
0
17
9
0
0
42
9
0
% D
% Glu:
17
9
0
0
67
0
9
0
42
17
0
0
9
17
9
% E
% Phe:
0
0
0
0
0
9
17
0
0
0
50
0
9
0
0
% F
% Gly:
0
9
0
9
0
0
0
17
9
0
17
0
0
9
42
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% H
% Ile:
0
0
17
0
0
0
42
9
17
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% K
% Leu:
25
17
9
0
0
59
9
9
9
50
9
9
17
0
0
% L
% Met:
9
0
9
0
9
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
17
0
0
0
34
0
0
9
% N
% Pro:
9
0
0
9
9
0
0
0
9
0
0
17
0
9
17
% P
% Gln:
17
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
17
9
9
0
0
0
0
0
0
0
9
0
9
0
0
% R
% Ser:
9
34
9
59
0
9
9
34
0
0
9
9
0
0
17
% S
% Thr:
0
9
50
17
0
0
0
0
0
9
0
9
9
0
0
% T
% Val:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _