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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLCN4 All Species: 17.58
Human Site: S610 Identified Species: 35.15
UniProt: P51793 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51793 NP_001821.2 760 84917 S610 R R G E P P L S V L T Q D S M
Chimpanzee Pan troglodytes XP_001154165 791 87957 A641 R R N D P P L A V L T Q D N M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848379 760 84902 S610 R R G E P P L S V L T Q D S M
Cat Felis silvestris
Mouse Mus musculus Q61418 747 83956 S597 R R E E P P L S V L T Q D S M
Rat Rattus norvegicus P51794 747 83683 S597 R R G E P P L S V L T Q D S M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515028 869 97095 S719 R R G E P P L S V L T Q D G M
Chicken Gallus gallus XP_425575 680 76203 E548 D V E T L I K E T D Y N G F P
Frog Xenopus laevis Q9W701 689 76782 I557 E E F M N P D I R V L P R E A
Zebra Danio Brachydanio rerio NP_001070786 768 85452 V619 R S E P P L S V L T Q D S S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGH7 1193 133629 R739 W Q K E A Q E R A L E E E K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92943 792 87043 R601 Q K V I S L P R V I R V A D V
Baker's Yeast Sacchar. cerevisiae P37020 779 87664 L611 L S E L E S L L Y D S A S E Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.2 N.A. 99.2 N.A. 96.3 97.3 N.A. 85 82.8 25.3 89 N.A. 20.2 N.A. N.A. N.A.
Protein Similarity: 100 85.5 N.A. 100 N.A. 97.5 98.1 N.A. 86.6 85.5 44.6 94.2 N.A. 34.4 N.A. N.A. N.A.
P-Site Identity: 100 73.3 N.A. 100 N.A. 93.3 100 N.A. 93.3 0 6.6 20 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 100 N.A. 93.3 100 N.A. 93.3 0 13.3 26.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.6 31.3 N.A.
Protein Similarity: N.A. N.A. N.A. 46.9 52.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 9 9 0 0 9 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 0 0 9 0 0 17 0 9 50 9 0 % D
% Glu: 9 9 34 50 9 0 9 9 0 0 9 9 9 17 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 34 0 0 0 0 0 0 0 0 0 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 9 0 9 0 9 0 0 0 0 0 % I
% Lys: 0 9 9 0 0 0 9 0 0 0 0 0 0 9 9 % K
% Leu: 9 0 0 9 9 17 59 9 9 59 9 0 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 50 % M
% Asn: 0 0 9 0 9 0 0 0 0 0 0 9 0 9 0 % N
% Pro: 0 0 0 9 59 59 9 0 0 0 0 9 0 0 9 % P
% Gln: 9 9 0 0 0 9 0 0 0 0 9 50 0 0 0 % Q
% Arg: 59 50 0 0 0 0 0 17 9 0 9 0 9 0 0 % R
% Ser: 0 17 0 0 9 9 9 42 0 0 9 0 17 42 0 % S
% Thr: 0 0 0 9 0 0 0 0 9 9 50 0 0 0 9 % T
% Val: 0 9 9 0 0 0 0 9 59 9 0 9 0 0 9 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _