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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN5
All Species:
31.52
Human Site:
S643
Identified Species:
57.78
UniProt:
P51795
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51795
NP_000075.1
746
83147
S643
L
R
R
D
L
I
I
S
I
E
N
A
R
K
K
Chimpanzee
Pan troglodytes
XP_001154165
791
87957
A688
L
R
R
D
L
T
I
A
I
E
S
A
R
K
K
Rhesus Macaque
Macaca mulatta
XP_001083068
746
83128
S643
L
R
R
D
L
I
I
S
I
E
N
A
R
K
K
Dog
Lupus familis
XP_549002
992
108374
S889
L
R
R
D
L
I
I
S
I
E
N
A
R
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVD4
746
83082
S643
L
R
R
D
L
I
I
S
I
E
N
A
R
K
K
Rat
Rattus norvegicus
P51796
746
83049
S643
L
R
R
D
L
I
I
S
I
E
N
A
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515028
869
97095
A766
Q
R
R
E
L
I
L
A
I
K
N
A
R
Q
R
Chicken
Gallus gallus
XP_420265
942
104254
S839
L
R
R
D
L
I
I
S
I
E
N
A
R
K
K
Frog
Xenopus laevis
NP_001080969
808
90050
S705
L
R
R
D
L
I
I
S
I
E
S
A
R
K
K
Zebra Danio
Brachydanio rerio
XP_001920783
811
89757
S708
Q
R
R
D
L
V
I
S
I
D
N
A
R
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
A946
K
F
K
A
N
K
V
A
D
V
N
R
S
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
P658
D
F
Q
H
S
P
L
P
C
D
P
S
A
R
N
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
I651
K
R
H
L
A
S
K
I
M
M
Q
S
V
N
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.6
99.7
74.2
N.A.
97.9
98.2
N.A.
66.5
71
79.2
76.6
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
83.3
100
74.9
N.A.
99.3
99.4
N.A.
76.8
75.3
85.6
84.4
N.A.
35.2
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
100
N.A.
53.3
100
93.3
66.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
100
100
93.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
32.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
53.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
24
0
0
0
77
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
0
0
70
0
0
0
0
8
16
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
62
0
0
0
0
0
% E
% Phe:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
62
70
8
77
0
0
0
0
0
0
% I
% Lys:
16
0
8
0
0
8
8
0
0
8
0
0
0
62
62
% K
% Leu:
62
0
0
8
77
0
16
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
70
0
0
8
8
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
8
0
0
8
0
% P
% Gln:
16
0
8
0
0
0
0
0
0
0
8
0
0
16
8
% Q
% Arg:
0
85
77
0
0
0
0
0
0
0
0
8
77
8
16
% R
% Ser:
0
0
0
0
8
8
0
62
0
0
16
16
8
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _