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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
13.64
Human Site:
S190
Identified Species:
23.08
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
S190
K
V
L
G
V
L
F
S
V
A
G
G
L
F
V
Chimpanzee
Pan troglodytes
XP_514393
802
89426
F150
V
G
A
G
L
P
Q
F
Q
S
I
S
L
R
K
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
S190
K
V
L
G
V
L
F
S
V
A
G
G
L
F
V
Dog
Lupus familis
XP_535404
889
99260
S209
K
V
F
G
V
L
F
S
V
A
G
G
L
F
V
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
S190
K
V
F
G
V
L
F
S
V
S
G
G
L
F
V
Rat
Rattus norvegicus
P51799
803
88712
G151
I
V
V
E
N
L
A
G
L
K
Y
R
V
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
P197
S
L
L
V
L
I
Q
P
V
A
A
G
S
G
I
Chicken
Gallus gallus
XP_417644
868
97172
V189
A
M
G
V
L
F
S
V
A
G
G
L
F
V
G
Frog
Xenopus laevis
Q9W701
689
76782
L37
R
R
V
V
I
D
H
L
Q
R
L
K
N
F
L
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
G189
G
V
L
F
A
V
A
G
G
L
F
V
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
K151
I
S
I
E
E
L
T
K
L
K
Y
G
H
M
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
P109
Y
L
N
G
V
K
V
P
H
V
V
R
L
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
T140
F
S
S
A
Y
I
I
T
Q
F
A
P
A
A
A
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
V127
C
N
G
V
V
N
E
V
T
S
T
S
N
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
13.3
100
93.3
N.A.
86.6
13.3
N.A.
26.6
6.6
6.6
13.3
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
33.3
N.A.
53.3
20
33.3
20
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
15
0
8
29
15
0
8
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
15
8
0
8
0
0
0
0
0
0
0
8
% E
% Phe:
8
0
15
8
0
8
29
8
0
8
8
0
8
36
0
% F
% Gly:
8
8
15
43
0
0
0
15
8
8
36
43
8
8
8
% G
% His:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% H
% Ile:
15
0
8
0
8
15
8
0
0
0
8
0
0
8
8
% I
% Lys:
29
0
0
0
0
8
0
8
0
15
0
8
0
15
15
% K
% Leu:
0
15
29
0
22
43
0
8
15
8
8
8
43
8
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
8
8
0
8
8
0
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
8
0
15
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
15
0
22
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
0
8
0
15
0
8
0
% R
% Ser:
8
15
8
0
0
0
8
29
0
22
0
15
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
8
0
8
0
0
0
8
% T
% Val:
8
43
15
29
43
8
8
15
36
8
8
8
8
8
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _