Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLCN6 All Species: 16.67
Human Site: S50 Identified Species: 28.21
UniProt: P51797 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51797 NP_001277.1 869 97217 S50 L P R K D Y E S L D Y D R C I
Chimpanzee Pan troglodytes XP_514393 802 89426 E10 N K K G R R Y E A V K W M V V
Rhesus Macaque Macaca mulatta XP_001104721 869 97094 S50 L P R K D Y E S L D Y D R C I
Dog Lupus familis XP_535404 889 99260 S69 L P R K D Y E S L D Y D R C I
Cat Felis silvestris
Mouse Mus musculus O35454 870 96962 S50 L P R K D Y E S L D Y D R C I
Rat Rattus norvegicus P51799 803 88712 S11 V S K K V S W S G R D R D D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516296 878 97865 H57 C P G S P G S H L T S D S S K
Chicken Gallus gallus XP_417644 868 97172 L49 P R K D Y E S L D Y D R C I N
Frog Xenopus laevis Q9W701 689 76782
Zebra Danio Brachydanio rerio XP_696527 863 96883 Y49 K D Y E S L D Y D R C I N E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396520 803 89642 S11 T P T H I N V S I N D S I D D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193438 761 83935
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92943 792 87043
Baker's Yeast Sacchar. cerevisiae P37020 779 87664
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.2 99.4 93.3 N.A. 96.7 40.8 N.A. 81.3 93.2 22.7 82.6 N.A. N.A. 37.9 N.A. 49.8
Protein Similarity: 100 92.2 99.8 95.1 N.A. 98.7 58 N.A. 85.3 97.8 39.1 90.7 N.A. N.A. 57.3 N.A. 64.6
P-Site Identity: 100 0 100 100 N.A. 100 13.3 N.A. 20 0 0 0 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 13.3 100 100 N.A. 100 26.6 N.A. 20 6.6 0 13.3 N.A. N.A. 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 30 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 48.6 42.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 0 8 29 0 % C
% Asp: 0 8 0 8 29 0 8 0 15 29 22 36 8 15 8 % D
% Glu: 0 0 0 8 0 8 29 8 0 0 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 8 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 8 8 8 29 % I
% Lys: 8 8 22 36 0 0 0 0 0 0 8 0 0 0 8 % K
% Leu: 29 0 0 0 0 8 0 8 36 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 8 0 0 8 0 8 % N
% Pro: 8 43 0 0 8 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 29 0 8 8 0 0 0 15 0 15 29 0 0 % R
% Ser: 0 8 0 8 8 8 15 43 0 0 8 8 8 8 0 % S
% Thr: 8 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % T
% Val: 8 0 0 0 8 0 8 0 0 8 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 8 0 8 29 8 8 0 8 29 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _