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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLCN7 All Species: 26.67
Human Site: S11 Identified Species: 45.13
UniProt: P51798 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51798 NP_001107803.1 805 88679 S11 V S K K V S W S G R D R D D E
Chimpanzee Pan troglodytes XP_001159424 805 88612 S11 V S K K V S W S G R D R D D E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537014 809 88988 S11 V S K K V S W S G R D L D D D
Cat Felis silvestris
Mouse Mus musculus O70496 803 88694 S11 V S K K V S W S G R D R D D E
Rat Rattus norvegicus P51799 803 88712 S11 V S K K V S W S G R D R D D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516953 776 85812 M11 S S A S R E L M S C D P D P C
Chicken Gallus gallus NP_001025815 802 88577 S11 V A K K V S W S G R D P R D D
Frog Xenopus laevis Q9W701 689 76782
Zebra Danio Brachydanio rerio NP_001071005 795 88330 S11 I T K K V S W S S R G D D R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396520 803 89642 C23 I D D S V D N C A N D C E N D
Nematode Worm Caenorhab. elegans NP_506022 796 89213 S11 R N R V R T S S N S L D P N E
Sea Urchin Strong. purpuratus XP_796968 803 89073 G11 A P L T P R P G G Q R M K S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92943 792 87043 E11 N H L Q N G I E S D N L L W S
Baker's Yeast Sacchar. cerevisiae P37020 779 87664 P11 T Y V P I N Q P I R D G E D V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 94.4 N.A. 96.4 96.2 N.A. 89.4 85.9 24.2 76.1 N.A. N.A. 51.4 46.7 55.2
Protein Similarity: 100 99.8 N.A. 97.6 N.A. 97.8 97.8 N.A. 93.1 92.1 42.1 86.2 N.A. N.A. 69.8 64.8 71.1
P-Site Identity: 100 100 N.A. 86.6 N.A. 100 100 N.A. 20 73.3 0 53.3 N.A. N.A. 13.3 13.3 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 20 86.6 0 66.6 N.A. N.A. 40 40 20
Percent
Protein Identity: N.A. N.A. N.A. 35.6 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.6 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 8 0 8 0 0 8 % C
% Asp: 0 8 8 0 0 8 0 0 0 8 65 15 50 50 22 % D
% Glu: 0 0 0 0 0 8 0 8 0 0 0 0 15 0 36 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 8 50 0 8 8 0 0 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 8 0 8 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 50 50 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 15 0 0 0 8 0 0 0 8 15 8 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % M
% Asn: 8 8 0 0 8 8 8 0 8 8 8 0 0 15 0 % N
% Pro: 0 8 0 8 8 0 8 8 0 0 0 15 8 8 0 % P
% Gln: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 8 % Q
% Arg: 8 0 8 0 15 8 0 0 0 58 8 29 8 8 0 % R
% Ser: 8 43 0 15 0 50 8 58 22 8 0 0 0 8 8 % S
% Thr: 8 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 43 0 8 8 58 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 50 0 0 0 0 0 0 8 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _