KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN7
All Species:
28.79
Human Site:
S445
Identified Species:
48.72
UniProt:
P51798
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51798
NP_001107803.1
805
88679
S445
C
Q
P
L
Q
G
G
S
M
S
Y
P
L
Q
L
Chimpanzee
Pan troglodytes
XP_001159424
805
88612
S445
C
Q
P
L
Q
G
G
S
M
S
Y
P
L
Q
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537014
809
88988
S449
C
Q
P
L
Q
G
S
S
V
S
Y
P
L
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
O70496
803
88694
S443
C
Q
P
L
Q
G
S
S
M
S
Y
P
L
Q
L
Rat
Rattus norvegicus
P51799
803
88712
S443
C
Q
P
L
Q
G
S
S
M
S
Y
P
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516953
776
85812
S416
C
Q
P
L
Q
G
N
S
M
S
Y
P
L
Q
L
Chicken
Gallus gallus
NP_001025815
802
88577
S441
C
Q
P
I
Q
G
S
S
V
A
Y
P
L
Q
L
Frog
Xenopus laevis
Q9W701
689
76782
A350
E
S
L
G
Q
F
L
A
S
R
L
T
M
K
E
Zebra Danio
Brachydanio rerio
NP_001071005
795
88330
T433
Q
P
L
G
P
D
H
T
E
E
Y
P
L
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
P437
C
K
P
L
G
Q
D
P
T
K
F
P
I
Q
M
Nematode Worm
Caenorhab. elegans
NP_506022
796
89213
T429
I
G
A
N
P
T
A
T
S
T
Q
I
N
Q
M
Sea Urchin
Strong. purpuratus
XP_796968
803
89073
N439
S
D
C
R
P
L
D
N
T
Q
F
P
L
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
G406
P
R
P
P
G
M
Y
G
N
Y
V
N
F
F
C
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
L408
M
T
E
S
M
G
I
L
F
H
E
C
V
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
94.4
N.A.
96.4
96.2
N.A.
89.4
85.9
24.2
76.1
N.A.
N.A.
51.4
46.7
55.2
Protein Similarity:
100
99.8
N.A.
97.6
N.A.
97.8
97.8
N.A.
93.1
92.1
42.1
86.2
N.A.
N.A.
69.8
64.8
71.1
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
93.3
73.3
6.6
33.3
N.A.
N.A.
33.3
6.6
26.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
26.6
40
N.A.
N.A.
60
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
8
0
8
0
0
0
0
0
% A
% Cys:
58
0
8
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
8
0
0
0
8
15
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
8
8
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
15
0
8
8
0
% F
% Gly:
0
8
0
15
15
58
15
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
8
0
0
0
0
8
8
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
0
0
0
15
0
% K
% Leu:
0
0
15
50
0
8
8
8
0
0
8
0
65
0
65
% L
% Met:
8
0
0
0
8
8
0
0
36
0
0
0
8
0
15
% M
% Asn:
0
0
0
8
0
0
8
8
8
0
0
8
8
0
8
% N
% Pro:
8
8
65
8
22
0
0
8
0
0
0
72
0
0
0
% P
% Gln:
8
50
0
0
58
8
0
0
0
8
8
0
0
79
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
8
0
8
0
0
29
50
15
43
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
8
0
15
15
8
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
15
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
58
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _