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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLCN7 All Species: 34.55
Human Site: S476 Identified Species: 58.46
UniProt: P51798 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51798 NP_001107803.1 805 88679 S476 T P E K S V V S L F H D P P G
Chimpanzee Pan troglodytes XP_001159424 805 88612 S476 T P E K S V V S L F H D P P G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537014 809 88988 S480 T P E K S V V S L F H D P P G
Cat Felis silvestris
Mouse Mus musculus O70496 803 88694 S474 T P E K S V V S L F H D P P G
Rat Rattus norvegicus P51799 803 88712 S474 T P E K S V V S L F H D P P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516953 776 85812 S447 T P E K S V V S L F H D P P G
Chicken Gallus gallus NP_001025815 802 88577 N472 T P E K S V V N L F H D P P G
Frog Xenopus laevis Q9W701 689 76782 S381 Q N S S L D R S P L V D P N N
Zebra Danio Brachydanio rerio NP_001071005 795 88330 S464 T P E R S V R S L F H N P P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396520 803 89642 S468 T P E S S V R S L F H D P K G
Nematode Worm Caenorhab. elegans NP_506022 796 89213 S460 N P E E S V K S M F H S P I N
Sea Urchin Strong. purpuratus XP_796968 803 89073 L470 T P E E S V K L L F H K E P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92943 792 87043 L437 Q D D A I R N L F S A K T M R
Baker's Yeast Sacchar. cerevisiae P37020 779 87664 K439 T H A F E F L K I F T S L C F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 94.4 N.A. 96.4 96.2 N.A. 89.4 85.9 24.2 76.1 N.A. N.A. 51.4 46.7 55.2
Protein Similarity: 100 99.8 N.A. 97.6 N.A. 97.8 97.8 N.A. 93.1 92.1 42.1 86.2 N.A. N.A. 69.8 64.8 71.1
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 93.3 20 80 N.A. N.A. 80 53.3 66.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 20 93.3 N.A. N.A. 80 66.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.6 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.6 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 8 8 0 0 8 0 0 0 0 0 65 0 0 0 % D
% Glu: 0 0 79 15 8 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 8 0 8 0 0 8 86 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 % G
% His: 0 8 0 0 0 0 0 0 0 0 79 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 0 0 0 50 0 0 15 8 0 0 0 15 0 8 0 % K
% Leu: 0 0 0 0 8 0 8 15 72 8 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % M
% Asn: 8 8 0 0 0 0 8 8 0 0 0 8 0 8 15 % N
% Pro: 0 79 0 0 0 0 0 0 8 0 0 0 79 65 0 % P
% Gln: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 8 22 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 8 15 79 0 0 72 0 8 0 15 0 0 0 % S
% Thr: 79 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % T
% Val: 0 0 0 0 0 79 50 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _