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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLCN7 All Species: 43.03
Human Site: S744 Identified Species: 72.82
UniProt: P51798 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51798 NP_001107803.1 805 88679 S744 L S E F M N P S P Y T V P Q E
Chimpanzee Pan troglodytes XP_001159424 805 88612 S744 L S E F M N P S P Y T V P Q E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537014 809 88988 S748 L S E F M N P S P Y T V P Q D
Cat Felis silvestris
Mouse Mus musculus O70496 803 88694 S742 L S E F M N P S P Y T V P Q E
Rat Rattus norvegicus P51799 803 88712 S742 L S E F M N P S P Y T V P Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516953 776 85812 S715 L T E F M N P S P Y T V P Q E
Chicken Gallus gallus NP_001025815 802 88577 S741 L S E F M N P S P Y T V P R E
Frog Xenopus laevis Q9W701 689 76782 T644 T F Q L S T W T S L H Q A H H
Zebra Danio Brachydanio rerio NP_001071005 795 88330 T734 L T E F M N P T P Y T V P Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396520 803 89642 S737 L R P F M N P S P Y T V Q H S
Nematode Worm Caenorhab. elegans NP_506022 796 89213 H731 I E P Y M H P H P H R V P L N
Sea Urchin Strong. purpuratus XP_796968 803 89073 S739 L R P F M N P S P Y S V R K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92943 792 87043 S707 L A P F L N P S P Y V V P E D
Baker's Yeast Sacchar. cerevisiae P37020 779 87664 L724 I V E E S G I L K G L V T A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 94.4 N.A. 96.4 96.2 N.A. 89.4 85.9 24.2 76.1 N.A. N.A. 51.4 46.7 55.2
Protein Similarity: 100 99.8 N.A. 97.6 N.A. 97.8 97.8 N.A. 93.1 92.1 42.1 86.2 N.A. N.A. 69.8 64.8 71.1
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 93.3 93.3 0 86.6 N.A. N.A. 66.6 33.3 60
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 13.3 100 N.A. N.A. 66.6 60 80
Percent
Protein Identity: N.A. N.A. N.A. 35.6 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.6 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. 60 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 % D
% Glu: 0 8 65 8 0 0 0 0 0 0 0 0 0 8 50 % E
% Phe: 0 8 0 79 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 8 0 8 8 0 0 15 8 % H
% Ile: 15 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 8 % K
% Leu: 79 0 0 8 8 0 0 8 0 8 8 0 0 8 0 % L
% Met: 0 0 0 0 79 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 79 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 29 0 0 0 86 0 86 0 0 0 72 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 8 8 50 0 % Q
% Arg: 0 15 0 0 0 0 0 0 0 0 8 0 8 8 0 % R
% Ser: 0 43 0 0 15 0 0 72 8 0 8 0 0 0 8 % S
% Thr: 8 15 0 0 0 8 0 15 0 0 65 0 8 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 8 93 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 79 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _