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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN7
All Species:
36.97
Human Site:
T226
Identified Species:
62.56
UniProt:
P51798
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51798
NP_001107803.1
805
88679
T226
P
H
V
V
R
L
K
T
L
V
I
K
V
S
G
Chimpanzee
Pan troglodytes
XP_001159424
805
88612
T226
P
H
V
V
R
L
K
T
L
V
I
K
V
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537014
809
88988
T230
P
H
V
V
R
L
K
T
L
V
I
K
V
S
G
Cat
Felis silvestris
Mouse
Mus musculus
O70496
803
88694
T224
P
H
V
V
R
L
K
T
L
V
I
K
V
S
G
Rat
Rattus norvegicus
P51799
803
88712
T224
P
H
V
V
R
L
K
T
L
V
I
K
V
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516953
776
85812
L198
H
V
V
R
L
K
T
L
V
I
K
V
C
G
V
Chicken
Gallus gallus
NP_001025815
802
88577
T222
P
H
V
V
R
L
K
T
L
V
I
K
V
C
G
Frog
Xenopus laevis
Q9W701
689
76782
G146
Y
L
T
I
K
N
F
G
A
K
V
V
G
L
T
Zebra Danio
Brachydanio rerio
NP_001071005
795
88330
T213
P
R
V
V
R
L
K
T
L
V
V
K
V
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
T220
P
R
V
V
R
I
K
T
L
A
V
K
T
I
G
Nematode Worm
Caenorhab. elegans
NP_506022
796
89213
T209
P
E
V
V
R
L
K
T
L
V
S
K
A
V
G
Sea Urchin
Strong. purpuratus
XP_796968
803
89073
T218
P
H
V
V
R
F
K
T
L
V
C
K
V
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
A200
G
P
L
V
H
T
G
A
C
I
A
S
L
L
G
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
K202
V
S
G
F
E
Y
N
K
E
F
L
G
L
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
94.4
N.A.
96.4
96.2
N.A.
89.4
85.9
24.2
76.1
N.A.
N.A.
51.4
46.7
55.2
Protein Similarity:
100
99.8
N.A.
97.6
N.A.
97.8
97.8
N.A.
93.1
92.1
42.1
86.2
N.A.
N.A.
69.8
64.8
71.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
93.3
0
80
N.A.
N.A.
60
73.3
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
93.3
20
86.6
N.A.
N.A.
73.3
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
8
0
8
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
8
8
0
0
8
0
0
0
8
0
% F
% Gly:
8
0
8
0
0
0
8
8
0
0
0
8
8
8
79
% G
% His:
8
50
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
15
43
0
0
8
0
% I
% Lys:
0
0
0
0
8
8
72
8
0
8
8
72
0
0
0
% K
% Leu:
0
8
8
0
8
58
0
8
72
0
8
0
15
22
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
72
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
8
72
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
8
8
0
36
0
% S
% Thr:
0
0
8
0
0
8
8
72
0
0
0
0
8
8
15
% T
% Val:
8
8
79
79
0
0
0
0
8
65
22
15
58
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _