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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN7
All Species:
30.3
Human Site:
Y156
Identified Species:
51.28
UniProt:
P51798
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51798
NP_001107803.1
805
88679
Y156
E
N
L
A
G
L
K
Y
R
V
I
K
G
N
I
Chimpanzee
Pan troglodytes
XP_001159424
805
88612
Y156
E
N
L
A
G
L
K
Y
R
V
I
K
G
N
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537014
809
88988
Y160
E
N
V
A
G
L
K
Y
K
I
V
K
D
N
I
Cat
Felis silvestris
Mouse
Mus musculus
O70496
803
88694
Y154
E
N
L
A
G
L
K
Y
R
V
I
K
D
N
I
Rat
Rattus norvegicus
P51799
803
88712
Y154
E
N
L
A
G
L
K
Y
R
V
I
K
D
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516953
776
85812
D135
R
V
V
K
D
N
I
D
K
F
T
E
K
G
G
Chicken
Gallus gallus
NP_001025815
802
88577
Y152
E
N
L
A
G
L
K
Y
R
V
V
K
D
N
I
Frog
Xenopus laevis
Q9W701
689
76782
Q83
L
N
A
H
R
W
L
Q
Q
E
L
G
G
N
V
Zebra Danio
Brachydanio rerio
NP_001071005
795
88330
Y143
E
N
L
A
G
L
K
Y
F
A
V
K
Q
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
T150
N
I
S
I
E
E
L
T
K
L
K
Y
G
H
M
Nematode Worm
Caenorhab. elegans
NP_506022
796
89213
L139
F
N
W
I
L
K
Y
L
L
S
K
C
G
E
E
Sea Urchin
Strong. purpuratus
XP_796968
803
89073
Y148
K
L
L
S
R
W
K
Y
Q
T
V
R
T
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
Y137
V
L
V
F
S
S
A
Y
I
I
T
Q
F
A
P
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
Q138
S
N
L
L
L
K
R
Q
E
F
E
C
E
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
94.4
N.A.
96.4
96.2
N.A.
89.4
85.9
24.2
76.1
N.A.
N.A.
51.4
46.7
55.2
Protein Similarity:
100
99.8
N.A.
97.6
N.A.
97.8
97.8
N.A.
93.1
92.1
42.1
86.2
N.A.
N.A.
69.8
64.8
71.1
P-Site Identity:
100
100
N.A.
66.6
N.A.
93.3
93.3
N.A.
0
86.6
20
73.3
N.A.
N.A.
6.6
13.3
20
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
20
93.3
40
80
N.A.
N.A.
33.3
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
50
0
0
8
0
0
8
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
0
29
0
0
% D
% Glu:
50
0
0
0
8
8
0
0
8
8
8
8
8
8
8
% E
% Phe:
8
0
0
8
0
0
0
0
8
15
0
0
8
0
8
% F
% Gly:
0
0
0
0
50
0
0
0
0
0
0
8
36
8
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
15
0
0
8
0
8
15
29
0
0
0
50
% I
% Lys:
8
0
0
8
0
15
58
0
22
0
15
50
8
0
0
% K
% Leu:
8
15
58
8
15
50
15
8
8
8
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
72
0
0
0
8
0
0
0
0
0
0
0
58
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
15
15
0
0
8
8
0
8
% Q
% Arg:
8
0
0
0
15
0
8
0
36
0
0
8
0
0
0
% R
% Ser:
8
0
8
8
8
8
0
0
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
15
0
8
0
0
% T
% Val:
8
8
22
0
0
0
0
0
0
36
29
0
0
0
8
% V
% Trp:
0
0
8
0
0
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
65
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _