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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN7
All Species:
42.73
Human Site:
Y406
Identified Species:
72.31
UniProt:
P51798
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51798
NP_001107803.1
805
88679
Y406
L
T
M
F
R
I
R
Y
I
H
R
P
C
L
Q
Chimpanzee
Pan troglodytes
XP_001159424
805
88612
Y406
L
T
M
F
R
I
R
Y
I
H
R
P
C
L
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537014
809
88988
Y410
L
T
M
F
R
I
R
Y
I
H
R
P
C
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
O70496
803
88694
Y404
L
T
M
F
R
I
R
Y
I
H
R
P
C
L
Q
Rat
Rattus norvegicus
P51799
803
88712
Y404
L
T
M
F
R
I
R
Y
I
H
R
P
C
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516953
776
85812
Y377
L
T
M
F
R
I
R
Y
I
H
R
P
C
L
Q
Chicken
Gallus gallus
NP_001025815
802
88577
Y402
L
T
M
F
R
I
R
Y
I
H
R
P
C
L
Q
Frog
Xenopus laevis
Q9W701
689
76782
N314
L
L
G
Y
V
R
R
N
S
L
T
S
K
L
L
Zebra Danio
Brachydanio rerio
NP_001071005
795
88330
Y393
L
T
I
F
R
I
R
Y
I
H
R
P
C
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
Y398
I
T
C
F
R
L
K
Y
I
K
K
K
W
L
K
Nematode Worm
Caenorhab. elegans
NP_506022
796
89213
Y387
L
T
E
F
R
K
K
Y
V
S
S
K
L
G
R
Sea Urchin
Strong. purpuratus
XP_796968
803
89073
Y400
L
T
I
F
R
M
K
Y
L
H
Y
S
W
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
C369
I
E
A
C
I
I
S
C
I
T
S
A
I
S
F
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
Y371
F
I
H
F
R
K
M
Y
L
S
S
W
P
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
94.4
N.A.
96.4
96.2
N.A.
89.4
85.9
24.2
76.1
N.A.
N.A.
51.4
46.7
55.2
Protein Similarity:
100
99.8
N.A.
97.6
N.A.
97.8
97.8
N.A.
93.1
92.1
42.1
86.2
N.A.
N.A.
69.8
64.8
71.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
20
93.3
N.A.
N.A.
40
33.3
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
26.6
100
N.A.
N.A.
73.3
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.6
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
8
8
0
0
0
8
0
0
0
0
58
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
86
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
65
0
0
0
0
0
% H
% Ile:
15
8
15
0
8
65
0
0
72
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
15
22
0
0
8
8
15
8
0
8
% K
% Leu:
79
8
0
0
0
8
0
0
15
8
0
0
8
72
8
% L
% Met:
0
0
50
0
0
8
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
58
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
72
% Q
% Arg:
0
0
0
0
86
8
65
0
0
0
58
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
8
0
8
15
22
15
0
15
0
% S
% Thr:
0
79
0
0
0
0
0
0
0
8
8
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
15
0
0
% W
% Tyr:
0
0
0
8
0
0
0
86
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _