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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLCN7 All Species: 34.55
Human Site: Y94 Identified Species: 58.46
UniProt: P51798 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51798 NP_001107803.1 805 88679 Y94 E K L L S L K Y E S L D Y D N
Chimpanzee Pan troglodytes XP_001159424 805 88612 Y94 E K L L S L K Y E S L D Y D N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537014 809 88988 Y98 E K L L S L K Y E S L D Y D N
Cat Felis silvestris
Mouse Mus musculus O70496 803 88694 Y92 E K L L S L K Y E S L D Y D N
Rat Rattus norvegicus P51799 803 88712 Y92 E K L L S L K Y E S L D Y D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516953 776 85812 F78 D N S E N Q L F L E E E R R I
Chicken Gallus gallus NP_001025815 802 88577 Y90 E K L L S L K Y E S L D Y D N
Frog Xenopus laevis Q9W701 689 76782 F26 Q K H I F R P F P N T R R V V
Zebra Danio Brachydanio rerio NP_001071005 795 88330 Y81 E K L L S L K Y E S L D Y D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396520 803 89642 Y92 T N F L S S N Y E S L D Y D P
Nematode Worm Caenorhab. elegans NP_506022 796 89213 L81 Y E I S E N R L Y R D A E K K
Sea Urchin Strong. purpuratus XP_796968 803 89073 Y84 M N V L S T K Y E S L D Y D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92943 792 87043 F78 Y Y V A V K W F F S L L I G I
Baker's Yeast Sacchar. cerevisiae P37020 779 87664 T78 D R A K T F I T L S S T A I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 94.4 N.A. 96.4 96.2 N.A. 89.4 85.9 24.2 76.1 N.A. N.A. 51.4 46.7 55.2
Protein Similarity: 100 99.8 N.A. 97.6 N.A. 97.8 97.8 N.A. 93.1 92.1 42.1 86.2 N.A. N.A. 69.8 64.8 71.1
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 0 100 6.6 100 N.A. N.A. 60 0 66.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 26.6 100 33.3 100 N.A. N.A. 60 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.6 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. 54.6 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 0 0 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 0 0 0 0 0 8 65 0 65 0 % D
% Glu: 50 8 0 8 8 0 0 0 65 8 8 8 8 0 8 % E
% Phe: 0 0 8 0 8 8 0 22 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 8 0 0 0 0 0 8 8 15 % I
% Lys: 0 58 0 8 0 8 58 0 0 0 0 0 0 8 8 % K
% Leu: 0 0 50 65 0 50 8 8 15 0 72 8 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 22 0 0 8 8 8 0 0 8 0 0 0 0 50 % N
% Pro: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 8 % P
% Gln: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 8 8 0 0 8 0 8 15 8 0 % R
% Ser: 0 0 8 8 65 8 0 0 0 79 8 0 0 0 0 % S
% Thr: 8 0 0 0 8 8 0 8 0 0 8 8 0 0 0 % T
% Val: 0 0 15 0 8 0 0 0 0 0 0 0 0 8 15 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 15 8 0 0 0 0 0 65 8 0 0 0 65 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _