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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCNKA
All Species:
31.21
Human Site:
S258
Identified Species:
62.42
UniProt:
P51800
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51800
NP_001036169.1
687
75285
S258
R
L
L
A
V
F
N
S
E
Q
E
T
I
T
S
Chimpanzee
Pan troglodytes
XP_525229
687
75266
S258
R
L
L
A
V
F
N
S
E
Q
E
T
I
T
S
Rhesus Macaque
Macaca mulatta
XP_001091784
740
81203
S258
R
L
L
A
V
F
N
S
E
Q
E
T
I
T
S
Dog
Lupus familis
XP_544547
687
75469
S258
R
L
L
A
V
F
N
S
E
Q
E
T
I
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUB7
687
75650
S258
R
L
L
A
V
F
N
S
E
Q
E
T
I
T
S
Rat
Rattus norvegicus
Q06393
687
75551
S258
R
L
L
G
V
F
N
S
E
Q
E
T
I
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425749
696
76448
S256
R
L
L
A
V
F
N
S
E
Q
E
T
I
A
A
Frog
Xenopus laevis
NP_001079308
689
76782
S259
R
L
L
A
V
F
N
S
E
Q
E
T
I
T
A
Zebra Danio
Brachydanio rerio
NP_956676
693
75983
G278
R
L
L
S
V
C
I
G
D
Q
D
T
I
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
Q378
R
L
L
A
V
W
F
Q
N
A
D
T
V
R
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P60300
763
83497
G286
L
I
D
V
C
L
S
G
K
C
G
L
F
G
K
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
A291
G
L
E
E
I
A
S
A
N
R
F
N
S
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
81.3
87.4
N.A.
82.5
83.2
N.A.
N.A.
60
61.9
43.5
N.A.
27.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
86.2
93
N.A.
90.8
91.2
N.A.
N.A.
73.5
78.5
62.1
N.A.
39.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
86.6
93.3
46.6
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
100
73.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
0
9
0
9
0
9
0
0
0
9
34
% A
% Cys:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
9
0
17
0
0
0
0
% D
% Glu:
0
0
9
9
0
0
0
0
67
0
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
67
9
0
0
0
9
0
9
0
0
% F
% Gly:
9
0
0
9
0
0
0
17
0
0
9
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
0
9
0
0
0
0
0
75
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% K
% Leu:
9
92
84
0
0
9
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
67
0
17
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
75
0
0
0
9
0
% Q
% Arg:
84
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% R
% Ser:
0
0
0
9
0
0
17
67
0
0
0
0
9
9
50
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
84
0
59
9
% T
% Val:
0
0
0
9
84
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _