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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAMP7 All Species: 25.76
Human Site: T173 Identified Species: 43.59
UniProt: P51809 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51809 NP_001138621.1 220 24935 T173 D S S V T F K T T S R N L A R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100063 182 21217 S136 T Q A Q K S C S S H V Y E E P
Dog Lupus familis XP_855489 331 37025 T284 D S S V T F K T T S R N L A R
Cat Felis silvestris
Mouse Mus musculus P70280 220 24949 T173 D S S V T F K T T S R N L A R
Rat Rattus norvegicus Q9JHW5 220 24757 T173 D S S V T F K T T S R N L A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514883 173 19669 V127 N K G T D R V V E T Q A Q V D
Chicken Gallus gallus Q5ZL74 220 24663 T173 D S S V T F K T T S R N L A R
Frog Xenopus laevis NP_001086871 220 24783 T173 D S S V T F K T T S R N L A R
Zebra Danio Brachydanio rerio Q7ZV15 215 24372 S168 E A L S A L D S K A S N L S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610524 218 24923 N166 N K T E N L S N N S V A F R K
Honey Bee Apis mellifera XP_623358 221 24793 K174 A N S V T F R K T S R N L A R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795809 220 25097 K174 T T S L T F K K S S K S L A R
Poplar Tree Populus trichocarpa XP_002298281 220 24836 K174 D G A F H F K K Q S K G L R R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FMR5 221 25298 K175 D S S F H F R K Q S K R L R R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 65.4 65.8 N.A. 97.2 95 N.A. 75.4 94 92.2 23.6 N.A. 51.8 58.8 N.A. 63.6
Protein Similarity: 100 N.A. 71.3 66.4 N.A. 99 98.1 N.A. 77.7 96.8 96.8 47.7 N.A. 75 76 N.A. 78.1
P-Site Identity: 100 N.A. 0 100 N.A. 100 100 N.A. 0 100 100 13.3 N.A. 6.6 73.3 N.A. 53.3
P-Site Similarity: 100 N.A. 20 100 N.A. 100 100 N.A. 20 100 100 46.6 N.A. 26.6 86.6 N.A. 86.6
Percent
Protein Identity: 41.8 N.A. N.A. 41.1 N.A. N.A.
Protein Similarity: 62.2 N.A. N.A. 61.9 N.A. N.A.
P-Site Identity: 40 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 53.3 N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 0 8 0 0 0 0 8 0 15 0 58 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 58 0 0 0 8 0 8 0 0 0 0 0 0 0 8 % D
% Glu: 8 0 0 8 0 0 0 0 8 0 0 0 8 8 0 % E
% Phe: 0 0 0 15 0 72 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 8 8 0 0 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 15 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 15 0 0 8 0 58 29 8 0 22 0 0 0 8 % K
% Leu: 0 0 8 8 0 15 0 0 0 0 0 0 79 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 8 0 0 8 0 0 8 8 0 0 58 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 8 0 8 0 0 0 0 15 0 8 0 8 0 0 % Q
% Arg: 0 0 0 0 0 8 15 0 0 0 50 8 0 22 72 % R
% Ser: 0 50 65 8 0 8 8 15 15 79 8 8 0 8 8 % S
% Thr: 15 8 8 8 58 0 0 43 50 8 0 0 0 0 0 % T
% Val: 0 0 0 50 0 0 8 8 0 0 15 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _