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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR143 All Species: 5.45
Human Site: S388 Identified Species: 12
UniProt: P51810 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51810 NP_000264.1 404 43878 S388 E I H T A S E S C N K N E G D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090139 407 44349 S391 E I H T A S E S C N K N E A D
Dog Lupus familis XP_548853 431 46929 Q407 Q P P P G H S Q V I Q T C L E
Cat Felis silvestris
Mouse Mus musculus P70259 405 44546 G388 V E I H T A T G S C N I K E V
Rat Rattus norvegicus NP_001100428 405 44505 G388 V E I H T A T G S H N I K E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514961 345 38370 A330 Y N L K D V D A T P E T Q G S
Chicken Gallus gallus XP_416848 392 43878 S377 M L S E G N T S S D D R L T R
Frog Xenopus laevis NP_001090311 400 45178 N383 L S I L S E G N G S I V E R L
Zebra Danio Brachydanio rerio NP_957116 412 45728 I388 S E S S T V E I H I S S E Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394576 250 28810 L235 I L S E S S P L L D P K F G C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175611 379 43439 D363 T N A A V P S D A E T T P L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.8 61.9 N.A. 77.2 75.5 N.A. 59.4 59.1 58.6 57.5 N.A. N.A. 20.7 N.A. 27.2
Protein Similarity: 100 N.A. 97.5 69.8 N.A. 84.4 83.4 N.A. 68.5 74.7 71.2 70.6 N.A. N.A. 34.6 N.A. 47.7
P-Site Identity: 100 N.A. 93.3 0 N.A. 0 0 N.A. 6.6 6.6 6.6 13.3 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 N.A. 93.3 20 N.A. 13.3 20 N.A. 33.3 26.6 26.6 26.6 N.A. N.A. 33.3 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 19 19 0 10 10 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 19 10 0 0 10 0 10 % C
% Asp: 0 0 0 0 10 0 10 10 0 19 10 0 0 0 19 % D
% Glu: 19 28 0 19 0 10 28 0 0 10 10 0 37 19 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 19 0 10 19 10 0 0 0 0 28 0 % G
% His: 0 0 19 19 0 10 0 0 10 10 0 0 0 0 0 % H
% Ile: 10 19 28 0 0 0 0 10 0 19 10 19 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 19 10 19 0 0 % K
% Leu: 10 19 10 10 0 0 0 10 10 0 0 0 10 19 10 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 19 0 0 0 10 0 10 0 19 19 19 0 0 0 % N
% Pro: 0 10 10 10 0 10 10 0 0 10 10 0 10 0 0 % P
% Gln: 10 0 0 0 0 0 0 10 0 0 10 0 10 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 19 % R
% Ser: 10 10 28 10 19 28 19 28 28 10 10 10 0 0 10 % S
% Thr: 10 0 0 19 28 0 28 0 10 0 10 28 0 10 0 % T
% Val: 19 0 0 0 10 19 0 0 10 0 0 10 0 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _