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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR143 All Species: 18.79
Human Site: T218 Identified Species: 41.33
UniProt: P51810 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51810 NP_000264.1 404 43878 T218 I L F Q K T V T A V A S L L K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001090139 407 44349 T218 I L F Q K T V T A V A S L L K
Dog Lupus familis XP_548853 431 46929 K234 D V S G S S L K P V R N A A K
Cat Felis silvestris
Mouse Mus musculus P70259 405 44546 T218 I L F H K T V T S V A S L L K
Rat Rattus norvegicus NP_001100428 405 44505 I218 I L F H K T V I S V A S L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514961 345 38370 I173 E R R L G A V I Q V R F F K I
Chicken Gallus gallus XP_416848 392 43878 T216 V L F R R T V T A V A S L L K
Frog Xenopus laevis NP_001090311 400 45178 A220 I L F R R T V A A V A S L L K
Zebra Danio Brachydanio rerio NP_957116 412 45728 S218 V L F T R T V S A V T S L L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394576 250 28810 S78 A N C H N L T S L S T A I L R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175611 379 43439 A203 E T I E P T M A C S A S A G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.8 61.9 N.A. 77.2 75.5 N.A. 59.4 59.1 58.6 57.5 N.A. N.A. 20.7 N.A. 27.2
Protein Similarity: 100 N.A. 97.5 69.8 N.A. 84.4 83.4 N.A. 68.5 74.7 71.2 70.6 N.A. N.A. 34.6 N.A. 47.7
P-Site Identity: 100 N.A. 100 13.3 N.A. 86.6 80 N.A. 13.3 80 80 66.6 N.A. N.A. 6.6 N.A. 20
P-Site Similarity: 100 N.A. 100 40 N.A. 93.3 86.6 N.A. 13.3 100 93.3 86.6 N.A. N.A. 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 19 46 0 64 10 19 10 0 % A
% Cys: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 19 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 64 0 0 0 0 0 0 0 0 10 10 0 0 % F
% Gly: 0 0 0 10 10 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 46 0 10 0 0 0 0 19 0 0 0 0 10 0 10 % I
% Lys: 0 0 0 0 37 0 0 10 0 0 0 0 0 10 73 % K
% Leu: 0 64 0 10 0 10 10 0 10 0 0 0 64 73 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 19 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 10 10 19 28 0 0 0 0 0 19 0 0 0 10 % R
% Ser: 0 0 10 0 10 10 0 19 19 19 0 73 0 0 0 % S
% Thr: 0 10 0 10 0 73 10 37 0 0 19 0 0 0 0 % T
% Val: 19 10 0 0 0 0 73 0 0 82 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _