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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR143
All Species:
24.55
Human Site:
Y178
Identified Species:
54
UniProt:
P51810
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51810
NP_000264.1
404
43878
Y178
E
G
A
A
M
L
Y
Y
P
S
V
S
R
C
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001090139
407
44349
Y178
E
G
A
A
M
L
Y
Y
P
S
V
S
R
C
E
Dog
Lupus familis
XP_548853
431
46929
A192
E
N
E
R
R
M
G
A
T
I
K
I
R
F
F
Cat
Felis silvestris
Mouse
Mus musculus
P70259
405
44546
Y178
E
G
A
V
M
L
Y
Y
P
S
V
S
R
C
E
Rat
Rattus norvegicus
NP_001100428
405
44505
Y178
E
G
A
V
M
L
Y
Y
P
S
V
S
R
C
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514961
345
38370
L135
T
T
Y
V
P
L
L
L
V
L
G
L
N
P
I
Chicken
Gallus gallus
XP_416848
392
43878
Y176
E
G
V
M
L
L
Y
Y
P
S
L
S
S
C
E
Frog
Xenopus laevis
NP_001090311
400
45178
Y180
E
G
V
A
M
L
Y
Y
P
S
V
S
N
C
E
Zebra Danio
Brachydanio rerio
NP_957116
412
45728
Y178
E
G
V
A
M
L
Y
Y
P
S
I
S
S
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394576
250
28810
R40
M
K
L
L
L
G
D
R
S
G
H
P
I
C
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175611
379
43439
L163
T
V
D
V
Y
L
F
L
Q
K
T
T
V
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.8
61.9
N.A.
77.2
75.5
N.A.
59.4
59.1
58.6
57.5
N.A.
N.A.
20.7
N.A.
27.2
Protein Similarity:
100
N.A.
97.5
69.8
N.A.
84.4
83.4
N.A.
68.5
74.7
71.2
70.6
N.A.
N.A.
34.6
N.A.
47.7
P-Site Identity:
100
N.A.
100
13.3
N.A.
93.3
93.3
N.A.
6.6
66.6
86.6
80
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
20
N.A.
93.3
93.3
N.A.
6.6
80
86.6
86.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
37
37
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
0
% C
% Asp:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
73
0
10
0
0
0
0
0
0
0
0
0
0
0
64
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% F
% Gly:
0
64
0
0
0
10
10
0
0
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
10
10
10
0
10
% I
% Lys:
0
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
10
10
19
82
10
19
0
10
10
10
0
0
0
% L
% Met:
10
0
0
10
55
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
19
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
64
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
10
0
0
0
0
46
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
64
0
64
19
0
0
% S
% Thr:
19
10
0
0
0
0
0
0
10
0
10
10
0
0
0
% T
% Val:
0
10
28
37
0
0
0
0
10
0
46
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
64
64
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _