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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY7
All Species:
13.64
Human Site:
S535
Identified Species:
27.27
UniProt:
P51828
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51828
NP_001105.1
1080
120308
S535
R
T
P
D
R
S
M
S
P
K
G
R
S
E
D
Chimpanzee
Pan troglodytes
XP_528648
1092
121760
S535
R
T
P
D
R
S
M
S
P
K
G
R
S
E
D
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
Q545
R
T
L
R
T
K
S
Q
K
K
R
F
E
E
E
Dog
Lupus familis
XP_544415
1067
119071
S535
R
T
P
D
R
S
A
S
P
K
G
R
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P51829
1099
122749
S537
R
A
P
D
R
S
A
S
P
K
G
R
L
E
D
Rat
Rattus norvegicus
P26769
1090
123297
Q544
R
T
L
R
T
K
S
Q
K
K
R
F
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
Q524
R
T
I
R
T
K
S
Q
K
K
R
F
E
E
E
Chicken
Gallus gallus
Q9DGG6
1334
149273
T644
Q
D
E
H
K
N
S
T
K
A
P
G
G
H
S
Frog
Xenopus laevis
P98999
1305
145393
A652
G
E
E
W
K
G
G
A
P
R
P
S
A
I
G
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
R592
R
T
K
S
Q
K
K
R
F
E
E
E
L
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
F758
C
W
G
A
D
R
P
F
A
N
I
A
E
S
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
C415
F
A
V
F
S
T
T
C
L
I
L
L
F
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
55.3
85.5
N.A.
82.5
55.2
N.A.
54.5
26.6
26.8
52.6
N.A.
35.4
N.A.
N.A.
38
Protein Similarity:
100
94.4
70.4
89.9
N.A.
88
70.1
N.A.
68.3
42.5
43.4
66.9
N.A.
49.5
N.A.
N.A.
52.5
P-Site Identity:
100
100
26.6
93.3
N.A.
80
26.6
N.A.
26.6
0
6.6
13.3
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
33.3
93.3
N.A.
80
33.3
N.A.
33.3
26.6
33.3
33.3
N.A.
0
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
0
0
17
9
9
9
0
9
9
0
0
% A
% Cys:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
34
9
0
0
0
0
0
0
0
0
0
34
% D
% Glu:
0
9
17
0
0
0
0
0
0
9
9
9
34
59
34
% E
% Phe:
9
0
0
9
0
0
0
9
9
0
0
25
9
0
0
% F
% Gly:
9
0
9
0
0
9
9
0
0
0
34
9
9
0
9
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
9
9
0
0
9
9
% I
% Lys:
0
0
9
0
17
34
9
0
34
59
0
0
0
0
9
% K
% Leu:
0
0
17
0
0
0
0
0
9
0
9
9
17
9
0
% L
% Met:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
9
0
0
0
9
0
% N
% Pro:
0
0
34
0
0
0
9
0
42
0
17
0
0
0
0
% P
% Gln:
9
0
0
0
9
0
0
25
0
0
0
0
0
0
0
% Q
% Arg:
67
0
0
25
34
9
0
9
0
9
25
34
0
0
0
% R
% Ser:
0
0
0
9
9
34
34
34
0
0
0
9
25
9
9
% S
% Thr:
0
59
0
0
25
9
9
9
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _