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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY7
All Species:
8.79
Human Site:
S540
Identified Species:
17.58
UniProt:
P51828
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51828
NP_001105.1
1080
120308
S540
S
M
S
P
K
G
R
S
E
D
D
S
Y
D
D
Chimpanzee
Pan troglodytes
XP_528648
1092
121760
S540
S
M
S
P
K
G
R
S
E
D
D
S
Y
D
D
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
E550
K
S
Q
K
K
R
F
E
E
E
L
N
E
R
M
Dog
Lupus familis
XP_544415
1067
119071
S540
S
A
S
P
K
G
R
S
E
D
D
S
Y
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P51829
1099
122749
L542
S
A
S
P
K
G
R
L
E
D
D
C
D
D
E
Rat
Rattus norvegicus
P26769
1090
123297
E549
K
S
Q
K
K
R
F
E
E
E
L
N
E
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
E529
K
S
Q
K
K
R
F
E
E
E
L
N
E
R
M
Chicken
Gallus gallus
Q9DGG6
1334
149273
G649
N
S
T
K
A
P
G
G
H
S
P
K
T
Q
N
Frog
Xenopus laevis
P98999
1305
145393
A657
G
G
A
P
R
P
S
A
I
G
A
S
L
K
D
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
L597
K
K
R
F
E
E
E
L
N
E
R
I
I
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
E763
R
P
F
A
N
I
A
E
S
K
L
V
K
N
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
F420
T
T
C
L
I
L
L
F
L
I
L
I
A
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
55.3
85.5
N.A.
82.5
55.2
N.A.
54.5
26.6
26.8
52.6
N.A.
35.4
N.A.
N.A.
38
Protein Similarity:
100
94.4
70.4
89.9
N.A.
88
70.1
N.A.
68.3
42.5
43.4
66.9
N.A.
49.5
N.A.
N.A.
52.5
P-Site Identity:
100
100
13.3
86.6
N.A.
66.6
13.3
N.A.
13.3
0
20
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
93.3
N.A.
73.3
26.6
N.A.
26.6
20
40
13.3
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
9
9
0
9
9
0
0
9
0
9
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
34
34
0
9
34
25
% D
% Glu:
0
0
0
0
9
9
9
34
59
34
0
0
25
0
17
% E
% Phe:
0
0
9
9
0
0
25
9
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
34
9
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
9
9
0
17
9
0
9
% I
% Lys:
34
9
0
34
59
0
0
0
0
9
0
9
9
9
0
% K
% Leu:
0
0
0
9
0
9
9
17
9
0
42
0
9
0
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
9
25
% M
% Asn:
9
0
0
0
9
0
0
0
9
0
0
25
0
9
9
% N
% Pro:
0
9
0
42
0
17
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
25
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
9
0
9
0
9
25
34
0
0
0
9
0
0
34
0
% R
% Ser:
34
34
34
0
0
0
9
25
9
9
0
34
0
0
0
% S
% Thr:
9
9
9
0
0
0
0
0
0
0
0
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _