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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY7
All Species:
19.39
Human Site:
Y25
Identified Species:
38.79
UniProt:
P51828
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51828
NP_001105.1
1080
120308
Y25
Q
D
A
L
Y
E
K
Y
Q
L
T
S
Q
H
G
Chimpanzee
Pan troglodytes
XP_528648
1092
121760
Y25
Q
D
A
L
Y
E
K
Y
Q
L
T
S
Q
H
G
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
Y37
R
D
W
L
Y
E
S
Y
Y
C
M
S
Q
Q
H
Dog
Lupus familis
XP_544415
1067
119071
Y25
Q
A
A
L
Y
G
K
Y
R
L
T
S
Q
H
G
Cat
Felis silvestris
Mouse
Mus musculus
P51829
1099
122749
Y25
Q
A
A
L
Y
E
K
Y
R
L
T
S
L
H
G
Rat
Rattus norvegicus
P26769
1090
123297
Y36
R
D
W
L
Y
E
S
Y
Y
C
M
S
Q
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
L25
N
V
V
G
G
M
A
L
F
E
I
P
D
G
D
Chicken
Gallus gallus
Q9DGG6
1334
149273
G65
S
G
G
V
G
R
G
G
G
G
G
L
R
R
Q
Frog
Xenopus laevis
P98999
1305
145393
C101
E
E
A
C
V
E
R
C
F
P
Q
T
Q
R
R
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
Y84
P
D
W
V
Y
E
S
Y
Y
R
M
S
Q
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
D26
A
N
L
I
V
K
A
D
G
N
A
T
Q
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
55.3
85.5
N.A.
82.5
55.2
N.A.
54.5
26.6
26.8
52.6
N.A.
35.4
N.A.
N.A.
38
Protein Similarity:
100
94.4
70.4
89.9
N.A.
88
70.1
N.A.
68.3
42.5
43.4
66.9
N.A.
49.5
N.A.
N.A.
52.5
P-Site Identity:
100
100
46.6
80
N.A.
80
46.6
N.A.
0
0
20
40
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
53.3
86.6
N.A.
86.6
53.3
N.A.
0
13.3
46.6
46.6
N.A.
33.3
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
42
0
0
0
17
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
9
0
17
0
0
0
0
0
% C
% Asp:
0
42
0
0
0
0
0
9
0
0
0
0
9
0
9
% D
% Glu:
9
9
0
0
0
59
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% F
% Gly:
0
9
9
9
17
9
9
9
17
9
9
0
0
9
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
25
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
34
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
9
50
0
0
0
9
0
34
0
9
9
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
25
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
9
0
9
0
9
0
% P
% Gln:
34
0
0
0
0
0
0
0
17
0
9
0
67
25
9
% Q
% Arg:
17
0
0
0
0
9
9
0
17
9
0
0
9
17
9
% R
% Ser:
9
0
0
0
0
0
25
0
0
0
0
59
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
34
17
0
0
0
% T
% Val:
0
9
9
17
17
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
59
0
0
59
25
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _