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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY7
All Species:
28.18
Human Site:
Y441
Identified Species:
56.36
UniProt:
P51828
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51828
NP_001105.1
1080
120308
Y441
H
G
Q
Q
R
D
P
Y
L
K
E
M
N
I
R
Chimpanzee
Pan troglodytes
XP_528648
1092
121760
Y441
H
G
Q
Q
R
D
P
Y
L
K
E
M
N
I
R
Rhesus Macaque
Macaca mulatta
XP_001083524
1091
123478
Y452
D
G
D
I
R
D
P
Y
L
K
Q
H
L
V
K
Dog
Lupus familis
XP_544415
1067
119071
Y441
H
G
Q
Q
R
D
P
Y
L
K
E
M
N
I
R
Cat
Felis silvestris
Mouse
Mus musculus
P51829
1099
122749
Y443
H
G
E
Q
R
D
P
Y
L
K
E
M
N
I
R
Rat
Rattus norvegicus
P26769
1090
123297
Y451
D
G
E
I
R
D
P
Y
L
K
Q
H
L
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519046
1069
121143
Y431
D
G
D
I
R
D
P
Y
L
K
E
H
Y
V
K
Chicken
Gallus gallus
Q9DGG6
1334
149273
Q545
K
V
T
E
R
V
G
Q
S
A
V
A
D
Q
L
Frog
Xenopus laevis
P98999
1305
145393
Q550
M
V
V
E
R
L
G
Q
I
V
A
A
D
Q
L
Zebra Danio
Brachydanio rerio
NP_001093457
1139
128958
Y499
N
G
Q
S
R
D
S
Y
L
K
E
H
G
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW60
1307
142798
Y479
E
G
G
N
R
D
A
Y
L
A
D
H
K
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780688
889
100312
V323
Q
Q
I
A
T
M
P
V
P
K
S
V
G
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
55.3
85.5
N.A.
82.5
55.2
N.A.
54.5
26.6
26.8
52.6
N.A.
35.4
N.A.
N.A.
38
Protein Similarity:
100
94.4
70.4
89.9
N.A.
88
70.1
N.A.
68.3
42.5
43.4
66.9
N.A.
49.5
N.A.
N.A.
52.5
P-Site Identity:
100
100
46.6
100
N.A.
93.3
46.6
N.A.
53.3
6.6
6.6
60
N.A.
33.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
66.6
100
N.A.
100
73.3
N.A.
66.6
20
26.6
66.6
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
0
0
17
9
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
0
17
0
0
75
0
0
0
0
9
0
17
0
0
% D
% Glu:
9
0
17
17
0
0
0
0
0
0
50
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
75
9
0
0
0
17
0
0
0
0
0
17
0
0
% G
% His:
34
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% H
% Ile:
0
0
9
25
0
0
0
0
9
0
0
0
0
42
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
75
0
0
9
0
25
% K
% Leu:
0
0
0
0
0
9
0
0
75
0
0
0
17
9
17
% L
% Met:
9
0
0
0
0
9
0
0
0
0
0
34
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
0
0
0
0
34
0
0
% N
% Pro:
0
0
0
0
0
0
67
0
9
0
0
0
0
0
0
% P
% Gln:
9
9
34
34
0
0
0
17
0
0
17
0
0
17
0
% Q
% Arg:
0
0
0
0
92
0
0
0
0
0
0
0
0
0
34
% R
% Ser:
0
0
0
9
0
0
9
0
9
0
9
0
0
0
0
% S
% Thr:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
17
9
0
0
9
0
9
0
9
9
9
0
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _