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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR0B1 All Species: 24.55
Human Site: Y378 Identified Species: 60
UniProt: P51843 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51843 NP_000466.2 470 51718 Y378 L N I S T K E Y A Y L K G T V
Chimpanzee Pan troglodytes Q9BG97 470 51692 Y378 L N I S T K E Y A Y L K G T V
Rhesus Macaque Macaca mulatta Q9BG93 470 51860 Y378 L N I S T K E Y A Y L K G T V
Dog Lupus familis XP_548923 471 51716 Y379 L D I S T K E Y A Y L K G T V
Cat Felis silvestris
Mouse Mus musculus Q61066 472 52558 Y380 L N I D T K E Y A Y L K G T V
Rat Rattus norvegicus P70503 472 52726 Y380 L N I D T K E Y A Y L K G T V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989924 263 29024 F180 Y L K G T V L F N P D L P G L
Frog Xenopus laevis Q6GN21 637 70767 Y533 L C V D G Y E Y A Y L K A I A
Zebra Danio Brachydanio rerio NP_001076416 264 29310 L181 A Y L K G A I L F N P D V A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26622 583 63834 F472 L D V D Q T E F A Y L K T I V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.6 74.5 N.A. 65.6 64.6 N.A. N.A. 40.6 22.6 32.5 N.A. N.A. N.A. N.A. 20
Protein Similarity: 100 99.5 99.3 82.1 N.A. 75.6 75 N.A. N.A. 47.4 35 40.8 N.A. N.A. N.A. N.A. 34.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 6.6 46.6 0 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 20 53.3 6.6 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 0 80 0 0 0 10 10 10 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 40 0 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 20 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 20 0 0 0 0 0 0 0 60 10 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 60 0 0 0 10 0 0 0 0 0 0 20 0 % I
% Lys: 0 0 10 10 0 60 0 0 0 0 0 80 0 0 0 % K
% Leu: 80 10 10 0 0 0 10 10 0 0 80 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 50 0 0 0 0 0 0 10 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 10 0 10 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 70 10 0 0 0 0 0 0 10 60 0 % T
% Val: 0 0 20 0 0 10 0 0 0 0 0 0 10 0 70 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 10 0 70 0 80 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _