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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASP5 All Species: 0
Human Site: T52 Identified Species: 0
UniProt: P51878 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.43
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51878 NP_001129581.1 434 49736 T52 I Q T L V P N T D Q K S T S V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q153Z0 421 47740 N37 L M E N N V L N T E E L R N L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P70343 373 42737 L14 P D K P L K V L E Q L G K E V
Rat Rattus norvegicus Q920D5 420 47818 L36 D L M D K N V L N G D E L L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509500 456 52101 D66 N I G V R Y F D V M Q G Y F G
Chicken Gallus gallus Q98943 424 47941 D39 M E H M I E K D I I T I E M V
Frog Xenopus laevis P55865 386 43644 D27 M I S D L L D D L R E K N V L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P42573 503 56598 I44 N S D N G D M I N S C G T V R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 44.2 N.A. N.A. 48.3 42.4 N.A. 44 26.2 40 N.A. N.A. N.A. N.A. 23.2 N.A.
Protein Similarity: 100 N.A. 61 N.A. N.A. 61.7 59.2 N.A. 59.6 44.2 56.4 N.A. N.A. N.A. N.A. 40.9 N.A.
P-Site Identity: 100 N.A. 0 N.A. N.A. 13.3 0 N.A. 0 6.6 0 N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. 33.3 N.A. N.A. 26.6 6.6 N.A. 13.3 33.3 46.6 N.A. N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 13 13 13 25 0 13 13 38 13 0 13 0 0 0 0 % D
% Glu: 0 13 13 0 0 13 0 0 13 13 25 13 13 13 0 % E
% Phe: 0 0 0 0 0 0 13 0 0 0 0 0 0 13 0 % F
% Gly: 0 0 13 0 13 0 0 0 0 13 0 38 0 0 13 % G
% His: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 25 0 0 13 0 0 13 13 13 0 13 0 0 0 % I
% Lys: 0 0 13 0 13 13 13 0 0 0 13 13 13 0 13 % K
% Leu: 13 13 0 13 25 13 13 25 13 0 13 13 13 13 25 % L
% Met: 25 13 13 13 0 0 13 0 0 13 0 0 0 13 0 % M
% Asn: 25 0 0 25 13 13 13 13 25 0 0 0 13 13 0 % N
% Pro: 13 0 0 13 0 13 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 13 0 0 0 0 0 0 0 25 13 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 13 0 0 13 0 13 % R
% Ser: 0 13 13 0 0 0 0 0 0 13 0 13 0 13 0 % S
% Thr: 0 0 13 0 0 0 0 13 13 0 13 0 25 0 0 % T
% Val: 0 0 0 13 13 13 25 0 13 0 0 0 0 25 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 0 0 0 0 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _