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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNH All Species: 33.94
Human Site: S230 Identified Species: 46.67
UniProt: P51946 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51946 NP_001230.1 323 37643 S230 R A G I T M E S Y L S E S L M
Chimpanzee Pan troglodytes XP_001145999 325 37922 S230 R A G I T M E S Y L S E S L M
Rhesus Macaque Macaca mulatta XP_001084672 323 37671 S230 R A G I T M E S Y L S E S L M
Dog Lupus familis XP_536300 402 46441 S309 R A G I T M E S Y L S E S L M
Cat Felis silvestris
Mouse Mus musculus Q61458 323 37488 S230 R A G I T M E S Y L S E S L M
Rat Rattus norvegicus Q9R1A0 323 37591 S230 R A G I T M E S Y L S E S L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510964 371 42563 S278 R A G I T M E S Y L S E S L M
Chicken Gallus gallus P55168 283 33240 L191 Y R T D L C L L Y P P F M I A
Frog Xenopus laevis P51947 323 37582 S230 R A G L N M E S Y L T E C L S
Zebra Danio Brachydanio rerio NP_001013471 319 37026 K227 S A A R A G L K M D V Y L N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524207 324 37758 T229 E N L D S Y V T D L L F V S A
Honey Bee Apis mellifera XP_393939 355 41233 N251 R A S A N L D N Y V T D I L F
Nematode Worm Caenorhab. elegans Q9TYP2 302 34995 D204 Q C Q K V A N D S L R C D V S
Sea Urchin Strong. purpuratus XP_787341 266 30836 T174 G L F I D I K T R F P A M K Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W5S1 336 38112 L235 G Q L A L A S L R I A N G V L
Baker's Yeast Sacchar. cerevisiae P37366 393 45192 T285 L V T R Y L E T K F P S R E G
Red Bread Mold Neurospora crassa Q9HE63 345 38453 A240 L A Q A Q A Q A Q A R A A M M
Conservation
Percent
Protein Identity: 100 96 99.3 78.1 N.A. 95 95.3 N.A. 73.3 24.7 71.2 65.6 N.A. 44.4 42.5 20.1 42.4
Protein Similarity: 100 96.6 100 79.5 N.A. 99 99.3 N.A. 81.1 43 84.8 83.2 N.A. 64.8 59.7 38.7 58.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 6.6 66.6 6.6 N.A. 6.6 26.6 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 80 6.6 N.A. 20 66.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 30.6 23.6 23.4
Protein Similarity: N.A. N.A. N.A. 53.2 41.7 43.1
P-Site Identity: N.A. N.A. N.A. 0 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 20 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 65 6 18 6 18 0 6 0 6 6 12 6 0 12 % A
% Cys: 0 6 0 0 0 6 0 0 0 0 0 6 6 0 0 % C
% Asp: 0 0 0 12 6 0 6 6 6 6 0 6 6 0 0 % D
% Glu: 6 0 0 0 0 0 53 0 0 0 0 48 0 6 6 % E
% Phe: 0 0 6 0 0 0 0 0 0 12 0 12 0 0 6 % F
% Gly: 12 0 48 0 0 6 0 0 0 0 0 0 6 0 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 48 0 6 0 0 0 6 0 0 6 6 0 % I
% Lys: 0 0 0 6 0 0 6 6 6 0 0 0 0 6 0 % K
% Leu: 12 6 12 6 12 12 12 12 0 59 6 0 6 53 6 % L
% Met: 0 0 0 0 0 48 0 0 6 0 0 0 12 6 48 % M
% Asn: 0 6 0 0 12 0 6 6 0 0 0 6 0 6 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 6 18 0 0 0 0 % P
% Gln: 6 6 12 0 6 0 6 0 6 0 0 0 0 0 6 % Q
% Arg: 53 6 0 12 0 0 0 0 12 0 12 0 6 0 0 % R
% Ser: 6 0 6 0 6 0 6 48 6 0 42 6 42 6 12 % S
% Thr: 0 0 12 0 42 0 0 18 0 0 12 0 0 0 0 % T
% Val: 0 6 0 0 6 0 6 0 0 6 6 0 6 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 6 6 0 0 59 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _