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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNH
All Species:
30.61
Human Site:
S246
Identified Species:
42.08
UniProt:
P51946
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51946
NP_001230.1
323
37643
S246
K
E
N
R
T
C
L
S
Q
L
L
D
I
M
K
Chimpanzee
Pan troglodytes
XP_001145999
325
37922
S246
K
E
N
R
T
C
L
S
Q
L
L
D
I
M
K
Rhesus Macaque
Macaca mulatta
XP_001084672
323
37671
S246
R
E
N
R
T
C
L
S
Q
L
L
D
I
M
K
Dog
Lupus familis
XP_536300
402
46441
S325
K
E
N
R
T
C
L
S
Q
L
L
D
I
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61458
323
37488
S246
K
E
N
R
T
C
L
S
Q
L
L
D
I
M
K
Rat
Rattus norvegicus
Q9R1A0
323
37591
S246
K
E
N
R
T
C
L
S
Q
L
L
D
I
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510964
371
42563
S294
K
E
N
R
T
C
M
S
Q
L
L
D
V
V
K
Chicken
Gallus gallus
P55168
283
33240
V207
A
C
L
H
V
A
C
V
V
Q
Q
K
D
A
R
Frog
Xenopus laevis
P51947
323
37582
S246
K
D
N
Q
E
T
M
S
H
L
L
D
G
M
R
Zebra Danio
Brachydanio rerio
NP_001013471
319
37026
E243
M
G
L
K
E
D
K
E
T
L
S
K
M
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524207
324
37758
D245
E
K
L
P
G
L
I
D
A
V
R
K
I
R
I
Honey Bee
Apis mellifera
XP_393939
355
41233
I267
K
E
H
L
G
C
I
I
E
A
V
R
K
I
R
Nematode Worm
Caenorhab. elegans
Q9TYP2
302
34995
G220
I
F
P
P
H
V
I
G
L
S
S
I
M
V
A
Sea Urchin
Strong. purpuratus
XP_787341
266
30836
E190
E
L
L
R
K
G
A
E
E
F
I
N
R
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W5S1
336
38112
L251
V
I
D
F
D
R
Y
L
E
N
I
V
S
Q
P
Baker's Yeast
Sacchar. cerevisiae
P37366
393
45192
E301
Q
E
S
V
P
G
N
E
K
E
E
P
Q
N
D
Red Bread Mold
Neurospora crassa
Q9HE63
345
38453
G256
G
G
G
Q
T
V
P
G
L
T
P
Q
S
S
S
Conservation
Percent
Protein Identity:
100
96
99.3
78.1
N.A.
95
95.3
N.A.
73.3
24.7
71.2
65.6
N.A.
44.4
42.5
20.1
42.4
Protein Similarity:
100
96.6
100
79.5
N.A.
99
99.3
N.A.
81.1
43
84.8
83.2
N.A.
64.8
59.7
38.7
58.8
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
80
0
46.6
6.6
N.A.
6.6
20
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
73.3
26.6
N.A.
33.3
60
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
23.6
23.4
Protein Similarity:
N.A.
N.A.
N.A.
53.2
41.7
43.1
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
6
6
0
6
6
0
0
0
6
6
% A
% Cys:
0
6
0
0
0
48
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
6
0
6
6
0
6
0
0
0
48
6
0
6
% D
% Glu:
12
53
0
0
12
0
0
18
18
6
6
0
0
0
6
% E
% Phe:
0
6
0
6
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
6
12
6
0
12
12
0
12
0
0
0
0
6
0
0
% G
% His:
0
0
6
6
6
0
0
0
6
0
0
0
0
0
0
% H
% Ile:
6
6
0
0
0
0
18
6
0
0
12
6
42
6
6
% I
% Lys:
48
6
0
6
6
0
6
0
6
0
0
18
6
0
42
% K
% Leu:
0
6
24
6
0
6
36
6
12
53
48
0
0
0
6
% L
% Met:
6
0
0
0
0
0
12
0
0
0
0
0
12
42
0
% M
% Asn:
0
0
48
0
0
0
6
0
0
6
0
6
0
6
0
% N
% Pro:
0
0
6
12
6
0
6
0
0
0
6
6
0
0
6
% P
% Gln:
6
0
0
12
0
0
0
0
42
6
6
6
6
6
0
% Q
% Arg:
6
0
0
48
0
6
0
0
0
0
6
6
6
6
18
% R
% Ser:
0
0
6
0
0
0
0
48
0
6
12
0
12
12
6
% S
% Thr:
0
0
0
0
48
6
0
0
6
6
0
0
0
0
0
% T
% Val:
6
0
0
6
6
12
0
6
6
6
6
6
6
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _