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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNH
All Species:
24.55
Human Site:
S267
Identified Species:
33.75
UniProt:
P51946
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51946
NP_001230.1
323
37643
S267
K
K
Y
E
P
P
R
S
E
E
V
A
V
L
K
Chimpanzee
Pan troglodytes
XP_001145999
325
37922
S267
K
K
Y
E
P
P
R
S
E
E
V
A
V
L
K
Rhesus Macaque
Macaca mulatta
XP_001084672
323
37671
S267
K
K
Y
E
P
P
R
S
E
E
V
A
V
L
K
Dog
Lupus familis
XP_536300
402
46441
S346
K
K
Y
E
P
P
R
S
E
E
V
A
A
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61458
323
37488
S267
K
K
Y
E
P
P
R
S
D
E
V
A
V
L
K
Rat
Rattus norvegicus
Q9R1A0
323
37591
S267
K
K
Y
E
P
P
R
S
E
E
V
A
I
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510964
371
42563
P315
K
K
Y
E
S
P
K
P
E
E
V
A
V
L
K
Chicken
Gallus gallus
P55168
283
33240
L228
S
V
D
M
E
K
I
L
E
I
I
R
V
I
L
Frog
Xenopus laevis
P51947
323
37582
P267
S
K
Y
E
P
A
R
P
E
E
V
A
A
L
K
Zebra Danio
Brachydanio rerio
NP_001013471
319
37026
L264
S
L
V
K
A
Y
E
L
P
K
A
E
E
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524207
324
37758
K266
Q
P
D
R
E
K
V
K
A
I
E
K
K
L
D
Honey Bee
Apis mellifera
XP_393939
355
41233
V288
D
P
P
S
R
E
M
V
R
A
L
E
K
K
L
Nematode Worm
Caenorhab. elegans
Q9TYP2
302
34995
L241
G
E
E
L
E
A
W
L
V
E
V
D
T
D
F
Sea Urchin
Strong. purpuratus
XP_787341
266
30836
A211
L
C
S
P
S
Q
I
A
L
A
A
L
V
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W5S1
336
38112
D272
S
E
L
T
K
L
L
D
N
I
E
Y
L
V
K
Baker's Yeast
Sacchar. cerevisiae
P37366
393
45192
S322
N
K
E
K
S
T
E
S
E
E
Y
S
I
D
S
Red Bread Mold
Neurospora crassa
Q9HE63
345
38453
E277
P
P
Q
S
P
A
G
E
G
P
A
E
G
N
K
Conservation
Percent
Protein Identity:
100
96
99.3
78.1
N.A.
95
95.3
N.A.
73.3
24.7
71.2
65.6
N.A.
44.4
42.5
20.1
42.4
Protein Similarity:
100
96.6
100
79.5
N.A.
99
99.3
N.A.
81.1
43
84.8
83.2
N.A.
64.8
59.7
38.7
58.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
13.3
73.3
0
N.A.
6.6
0
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
26.6
73.3
20
N.A.
13.3
6.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
23.6
23.4
Protein Similarity:
N.A.
N.A.
N.A.
53.2
41.7
43.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
18
0
6
6
12
18
48
12
0
0
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
12
0
0
0
0
6
6
0
0
6
0
12
6
% D
% Glu:
0
12
12
48
18
6
12
6
53
59
12
18
6
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
6
0
0
0
0
0
6
0
6
0
0
0
6
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
18
6
0
12
6
0
% I
% Lys:
42
53
0
12
6
12
6
6
0
6
0
6
12
6
59
% K
% Leu:
6
6
6
6
0
6
6
18
6
0
6
6
6
53
12
% L
% Met:
0
0
0
6
0
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
0
0
6
0
0
0
0
6
0
% N
% Pro:
6
18
6
6
48
42
0
12
6
6
0
0
0
0
0
% P
% Gln:
6
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
6
6
0
42
0
6
0
0
6
0
0
0
% R
% Ser:
24
0
6
12
18
0
0
42
0
0
0
6
0
6
18
% S
% Thr:
0
0
0
6
0
6
0
0
0
0
0
0
6
0
0
% T
% Val:
0
6
6
0
0
0
6
6
6
0
53
0
42
12
0
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
48
0
0
6
0
0
0
0
6
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _