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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNH All Species: 24.55
Human Site: S267 Identified Species: 33.75
UniProt: P51946 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51946 NP_001230.1 323 37643 S267 K K Y E P P R S E E V A V L K
Chimpanzee Pan troglodytes XP_001145999 325 37922 S267 K K Y E P P R S E E V A V L K
Rhesus Macaque Macaca mulatta XP_001084672 323 37671 S267 K K Y E P P R S E E V A V L K
Dog Lupus familis XP_536300 402 46441 S346 K K Y E P P R S E E V A A L K
Cat Felis silvestris
Mouse Mus musculus Q61458 323 37488 S267 K K Y E P P R S D E V A V L K
Rat Rattus norvegicus Q9R1A0 323 37591 S267 K K Y E P P R S E E V A I L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510964 371 42563 P315 K K Y E S P K P E E V A V L K
Chicken Gallus gallus P55168 283 33240 L228 S V D M E K I L E I I R V I L
Frog Xenopus laevis P51947 323 37582 P267 S K Y E P A R P E E V A A L K
Zebra Danio Brachydanio rerio NP_001013471 319 37026 L264 S L V K A Y E L P K A E E V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524207 324 37758 K266 Q P D R E K V K A I E K K L D
Honey Bee Apis mellifera XP_393939 355 41233 V288 D P P S R E M V R A L E K K L
Nematode Worm Caenorhab. elegans Q9TYP2 302 34995 L241 G E E L E A W L V E V D T D F
Sea Urchin Strong. purpuratus XP_787341 266 30836 A211 L C S P S Q I A L A A L V S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W5S1 336 38112 D272 S E L T K L L D N I E Y L V K
Baker's Yeast Sacchar. cerevisiae P37366 393 45192 S322 N K E K S T E S E E Y S I D S
Red Bread Mold Neurospora crassa Q9HE63 345 38453 E277 P P Q S P A G E G P A E G N K
Conservation
Percent
Protein Identity: 100 96 99.3 78.1 N.A. 95 95.3 N.A. 73.3 24.7 71.2 65.6 N.A. 44.4 42.5 20.1 42.4
Protein Similarity: 100 96.6 100 79.5 N.A. 99 99.3 N.A. 81.1 43 84.8 83.2 N.A. 64.8 59.7 38.7 58.8
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 80 13.3 73.3 0 N.A. 6.6 0 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 86.6 26.6 73.3 20 N.A. 13.3 6.6 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 23.6 23.4
Protein Similarity: N.A. N.A. N.A. 53.2 41.7 43.1
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 13.3
P-Site Similarity: N.A. N.A. N.A. 26.6 46.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 6 18 0 6 6 12 18 48 12 0 0 % A
% Cys: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 12 0 0 0 0 6 6 0 0 6 0 12 6 % D
% Glu: 0 12 12 48 18 6 12 6 53 59 12 18 6 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % F
% Gly: 6 0 0 0 0 0 6 0 6 0 0 0 6 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 12 0 0 18 6 0 12 6 0 % I
% Lys: 42 53 0 12 6 12 6 6 0 6 0 6 12 6 59 % K
% Leu: 6 6 6 6 0 6 6 18 6 0 6 6 6 53 12 % L
% Met: 0 0 0 6 0 0 6 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 0 0 0 0 0 6 0 0 0 0 6 0 % N
% Pro: 6 18 6 6 48 42 0 12 6 6 0 0 0 0 0 % P
% Gln: 6 0 6 0 0 6 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 6 6 0 42 0 6 0 0 6 0 0 0 % R
% Ser: 24 0 6 12 18 0 0 42 0 0 0 6 0 6 18 % S
% Thr: 0 0 0 6 0 6 0 0 0 0 0 0 6 0 0 % T
% Val: 0 6 6 0 0 0 6 6 6 0 53 0 42 12 0 % V
% Trp: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 48 0 0 6 0 0 0 0 6 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _