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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNH
All Species:
35.76
Human Site:
Y178
Identified Species:
49.17
UniProt:
P51946
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51946
NP_001230.1
323
37643
Y178
L
I
D
L
K
T
R
Y
P
I
L
E
N
P
E
Chimpanzee
Pan troglodytes
XP_001145999
325
37922
Y178
L
I
D
L
K
T
R
Y
P
I
L
E
N
P
E
Rhesus Macaque
Macaca mulatta
XP_001084672
323
37671
Y178
L
I
D
L
K
T
R
Y
P
M
L
E
N
P
E
Dog
Lupus familis
XP_536300
402
46441
Y257
L
I
D
L
K
T
R
Y
P
M
M
E
N
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61458
323
37488
Y178
L
I
D
I
K
T
R
Y
P
M
L
E
N
P
E
Rat
Rattus norvegicus
Q9R1A0
323
37591
Y178
L
I
D
I
K
T
R
Y
P
M
L
E
N
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510964
371
42563
Y226
L
I
D
L
K
T
R
Y
P
L
L
E
N
P
E
Chicken
Gallus gallus
P55168
283
33240
E139
M
N
H
I
L
E
C
E
F
Y
L
L
E
L
M
Frog
Xenopus laevis
P51947
323
37582
Y178
L
I
D
V
K
T
R
Y
P
M
L
E
N
P
E
Zebra Danio
Brachydanio rerio
NP_001013471
319
37026
K175
E
G
F
L
I
D
L
K
T
R
Y
P
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524207
324
37758
M177
D
I
K
T
R
S
N
M
Q
N
P
D
R
L
R
Honey Bee
Apis mellifera
XP_393939
355
41233
Y199
M
I
D
I
K
T
R
Y
T
S
L
E
N
P
E
Nematode Worm
Caenorhab. elegans
Q9TYP2
302
34995
E152
D
S
E
F
I
L
V
E
I
L
D
C
C
L
V
Sea Urchin
Strong. purpuratus
XP_787341
266
30836
I122
V
E
E
F
N
V
S
I
S
Q
F
C
G
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W5S1
336
38112
G183
A
P
Y
R
A
I
E
G
F
V
N
N
M
E
E
Baker's Yeast
Sacchar. cerevisiae
P37366
393
45192
V233
Q
N
V
L
Y
G
K
V
D
L
N
Y
M
G
Q
Red Bread Mold
Neurospora crassa
Q9HE63
345
38453
L188
N
D
H
Y
M
T
D
L
P
L
L
H
P
P
H
Conservation
Percent
Protein Identity:
100
96
99.3
78.1
N.A.
95
95.3
N.A.
73.3
24.7
71.2
65.6
N.A.
44.4
42.5
20.1
42.4
Protein Similarity:
100
96.6
100
79.5
N.A.
99
99.3
N.A.
81.1
43
84.8
83.2
N.A.
64.8
59.7
38.7
58.8
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
93.3
6.6
86.6
13.3
N.A.
6.6
73.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
100
13.3
N.A.
26.6
86.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
23.6
23.4
Protein Similarity:
N.A.
N.A.
N.A.
53.2
41.7
43.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
6
0
0
0
0
12
6
0
0
% C
% Asp:
12
6
53
0
0
6
6
0
6
0
6
6
0
0
0
% D
% Glu:
6
6
12
0
0
6
6
12
0
0
0
53
6
6
65
% E
% Phe:
0
0
6
12
0
0
0
0
12
0
6
0
0
0
0
% F
% Gly:
0
6
0
0
0
6
0
6
0
0
0
0
6
6
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
6
0
0
6
% H
% Ile:
0
59
0
24
12
6
0
6
6
12
0
0
0
0
0
% I
% Lys:
0
0
6
0
53
0
6
6
0
0
0
0
0
0
0
% K
% Leu:
48
0
0
42
6
6
6
6
0
24
59
6
6
24
6
% L
% Met:
12
0
0
0
6
0
0
6
0
30
6
0
12
0
6
% M
% Asn:
6
12
0
0
6
0
6
0
0
6
12
6
53
6
0
% N
% Pro:
0
6
0
0
0
0
0
0
53
0
6
6
6
59
0
% P
% Gln:
6
0
0
0
0
0
0
0
6
6
0
0
0
0
6
% Q
% Arg:
0
0
0
6
6
0
53
0
0
6
0
0
6
0
6
% R
% Ser:
0
6
0
0
0
6
6
0
6
6
0
0
0
0
0
% S
% Thr:
0
0
0
6
0
59
0
0
12
0
0
0
0
0
0
% T
% Val:
6
0
6
6
0
6
6
6
0
6
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
6
6
0
0
53
0
6
6
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _