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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNH All Species: 35.76
Human Site: Y178 Identified Species: 49.17
UniProt: P51946 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51946 NP_001230.1 323 37643 Y178 L I D L K T R Y P I L E N P E
Chimpanzee Pan troglodytes XP_001145999 325 37922 Y178 L I D L K T R Y P I L E N P E
Rhesus Macaque Macaca mulatta XP_001084672 323 37671 Y178 L I D L K T R Y P M L E N P E
Dog Lupus familis XP_536300 402 46441 Y257 L I D L K T R Y P M M E N P E
Cat Felis silvestris
Mouse Mus musculus Q61458 323 37488 Y178 L I D I K T R Y P M L E N P E
Rat Rattus norvegicus Q9R1A0 323 37591 Y178 L I D I K T R Y P M L E N P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510964 371 42563 Y226 L I D L K T R Y P L L E N P E
Chicken Gallus gallus P55168 283 33240 E139 M N H I L E C E F Y L L E L M
Frog Xenopus laevis P51947 323 37582 Y178 L I D V K T R Y P M L E N P E
Zebra Danio Brachydanio rerio NP_001013471 319 37026 K175 E G F L I D L K T R Y P L L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524207 324 37758 M177 D I K T R S N M Q N P D R L R
Honey Bee Apis mellifera XP_393939 355 41233 Y199 M I D I K T R Y T S L E N P E
Nematode Worm Caenorhab. elegans Q9TYP2 302 34995 E152 D S E F I L V E I L D C C L V
Sea Urchin Strong. purpuratus XP_787341 266 30836 I122 V E E F N V S I S Q F C G N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W5S1 336 38112 G183 A P Y R A I E G F V N N M E E
Baker's Yeast Sacchar. cerevisiae P37366 393 45192 V233 Q N V L Y G K V D L N Y M G Q
Red Bread Mold Neurospora crassa Q9HE63 345 38453 L188 N D H Y M T D L P L L H P P H
Conservation
Percent
Protein Identity: 100 96 99.3 78.1 N.A. 95 95.3 N.A. 73.3 24.7 71.2 65.6 N.A. 44.4 42.5 20.1 42.4
Protein Similarity: 100 96.6 100 79.5 N.A. 99 99.3 N.A. 81.1 43 84.8 83.2 N.A. 64.8 59.7 38.7 58.8
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 93.3 6.6 86.6 13.3 N.A. 6.6 73.3 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 20 100 13.3 N.A. 26.6 86.6 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 30.6 23.6 23.4
Protein Similarity: N.A. N.A. N.A. 53.2 41.7 43.1
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 26.6
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 6 0 0 0 0 12 6 0 0 % C
% Asp: 12 6 53 0 0 6 6 0 6 0 6 6 0 0 0 % D
% Glu: 6 6 12 0 0 6 6 12 0 0 0 53 6 6 65 % E
% Phe: 0 0 6 12 0 0 0 0 12 0 6 0 0 0 0 % F
% Gly: 0 6 0 0 0 6 0 6 0 0 0 0 6 6 0 % G
% His: 0 0 12 0 0 0 0 0 0 0 0 6 0 0 6 % H
% Ile: 0 59 0 24 12 6 0 6 6 12 0 0 0 0 0 % I
% Lys: 0 0 6 0 53 0 6 6 0 0 0 0 0 0 0 % K
% Leu: 48 0 0 42 6 6 6 6 0 24 59 6 6 24 6 % L
% Met: 12 0 0 0 6 0 0 6 0 30 6 0 12 0 6 % M
% Asn: 6 12 0 0 6 0 6 0 0 6 12 6 53 6 0 % N
% Pro: 0 6 0 0 0 0 0 0 53 0 6 6 6 59 0 % P
% Gln: 6 0 0 0 0 0 0 0 6 6 0 0 0 0 6 % Q
% Arg: 0 0 0 6 6 0 53 0 0 6 0 0 6 0 6 % R
% Ser: 0 6 0 0 0 6 6 0 6 6 0 0 0 0 0 % S
% Thr: 0 0 0 6 0 59 0 0 12 0 0 0 0 0 0 % T
% Val: 6 0 6 6 0 6 6 6 0 6 0 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 6 6 0 0 53 0 6 6 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _