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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2E1 All Species: 15.15
Human Site: S2 Identified Species: 23.81
UniProt: P51965 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51965 NP_003332.1 193 21404 S2 _ _ _ _ _ _ M S D D D S R A S
Chimpanzee Pan troglodytes XP_001173077 355 37792 S156 W G G G F A M S D D D S R A S
Rhesus Macaque Macaca mulatta XP_001100742 207 22864 S16 D D E S P S T S S G S S D A D
Dog Lupus familis XP_852428 205 22637 D9 S T E A Q R V D D S P S T S G
Cat Felis silvestris
Mouse Mus musculus P52482 193 21315 S2 _ _ _ _ _ _ M S D D D S R A S
Rat Rattus norvegicus P62839 147 16717
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509467 201 22210 D10 T E G Q R V D D S P S T S G G
Chicken Gallus gallus XP_418752 193 21359 S2 _ _ _ _ _ _ M S D D D S R A S
Frog Xenopus laevis NP_001088048 201 22153 D10 T E G Q R V D D S P S T S G G
Zebra Danio Brachydanio rerio NP_001096586 195 21461 E4 _ _ _ _ M S D E D S R A S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52485 232 24417 T41 S N T S Q P T T A G T P Q A R
Honey Bee Apis mellifera XP_395589 288 32000 S97 W D L P R F R S L V L K A M S
Nematode Worm Caenorhab. elegans P35129 147 16687
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P35134 148 16533
Baker's Yeast Sacchar. cerevisiae P15732 148 16262
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.3 77.2 73.6 N.A. 98.9 50.2 N.A. 83 99.4 82.5 88.7 N.A. 66.3 54.8 50.7 N.A.
Protein Similarity: 100 54.3 85 82.4 N.A. 99.4 59.5 N.A. 87.5 100 87.5 93.8 N.A. 73.7 61.1 60 N.A.
P-Site Identity: 100 60 20 13.3 N.A. 100 0 N.A. 0 100 0 18.1 N.A. 6.6 13.3 0 N.A.
P-Site Similarity: 100 80 20 26.6 N.A. 100 0 N.A. 13.3 100 13.3 36.3 N.A. 20 13.3 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 48.1 49.7 N.A.
Protein Similarity: N.A. N.A. N.A. 61.1 61.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 7 0 0 7 0 0 7 7 40 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 14 0 0 0 0 20 20 40 27 27 0 7 0 7 % D
% Glu: 0 14 14 0 0 0 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 20 7 0 0 0 0 0 14 0 0 0 14 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 0 7 0 0 0 0 0 7 0 7 0 0 0 0 % L
% Met: 0 0 0 0 7 0 27 0 0 0 0 0 0 7 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 7 7 0 0 0 14 7 7 0 0 0 % P
% Gln: 0 0 0 14 14 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 20 7 7 0 0 0 7 0 27 0 7 % R
% Ser: 14 0 0 14 0 14 0 40 20 14 20 40 20 14 40 % S
% Thr: 14 7 7 0 0 0 14 7 0 0 7 14 7 0 0 % T
% Val: 0 0 0 0 0 14 7 0 0 7 0 0 0 0 0 % V
% Trp: 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 27 27 27 27 20 20 0 0 0 0 0 0 0 0 0 % _