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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2E1 All Species: 43.94
Human Site: Y106 Identified Species: 69.05
UniProt: P51965 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51965 NP_003332.1 193 21404 Y106 D I T F T P E Y P F K P P K V
Chimpanzee Pan troglodytes XP_001173077 355 37792 Y260 D I T F T P E Y P F K P P K A
Rhesus Macaque Macaca mulatta XP_001100742 207 22864 Y120 D I T F S S D Y P F K P P K V
Dog Lupus familis XP_852428 205 22637 Y113 D I T F S P D Y P F K P P K V
Cat Felis silvestris
Mouse Mus musculus P52482 193 21315 Y106 D I T F T P E Y P F K P P K V
Rat Rattus norvegicus P62839 147 16717 P61 I H F P T D Y P F K P P K V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509467 201 22210 Y114 D I T F S P D Y P F K P P K V
Chicken Gallus gallus XP_418752 193 21359 Y106 D I T F T P E Y P F K P P K V
Frog Xenopus laevis NP_001088048 201 22153 Y114 D I T F S P D Y P F K P P K V
Zebra Danio Brachydanio rerio NP_001096586 195 21461 Y108 D I A F T P D Y P F K P P K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52485 232 24417 Y145 D I H F S P E Y P F K P P K V
Honey Bee Apis mellifera XP_395589 288 32000 Y201 D I H F S P E Y P F K P P K V
Nematode Worm Caenorhab. elegans P35129 147 16687 P61 I H F P T D Y P F K P P K V A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P35134 148 16533 F62 H F P P D Y P F K P P K V S F
Baker's Yeast Sacchar. cerevisiae P15732 148 16262 P62 I H F P T D Y P F K P P K V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.3 77.2 73.6 N.A. 98.9 50.2 N.A. 83 99.4 82.5 88.7 N.A. 66.3 54.8 50.7 N.A.
Protein Similarity: 100 54.3 85 82.4 N.A. 99.4 59.5 N.A. 87.5 100 87.5 93.8 N.A. 73.7 61.1 60 N.A.
P-Site Identity: 100 93.3 80 86.6 N.A. 100 13.3 N.A. 86.6 100 86.6 86.6 N.A. 86.6 86.6 13.3 N.A.
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 13.3 N.A. 100 100 100 93.3 N.A. 93.3 93.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 48.1 49.7 N.A.
Protein Similarity: N.A. N.A. N.A. 61.1 61.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 74 0 0 0 7 20 34 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 40 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 20 74 0 0 0 7 20 74 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 7 20 14 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 74 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 7 20 74 7 20 74 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 7 27 0 67 7 20 74 7 27 94 74 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 40 7 0 0 0 0 0 0 0 7 0 % S
% Thr: 0 0 54 0 54 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 7 20 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 20 74 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _