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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGD All Species: 39.09
Human Site: S230 Identified Species: 78.18
UniProt: P52209 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52209 NP_002622.2 483 53140 S230 W N K T E L D S F L I E I T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535411 483 53077 S230 W N K T E L D S F L I E I T A
Cat Felis silvestris
Mouse Mus musculus Q9DCD0 483 53229 S230 W N K T E L D S F L I E I T A
Rat Rattus norvegicus P85968 483 53218 S230 W N K T E L D S F L I E I T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509796 644 70224 S391 W N K T E L D S F L I E I T A
Chicken Gallus gallus NP_001006303 483 53274 S230 W N N T E L D S F L I E I T A
Frog Xenopus laevis NP_001083291 482 53549 S229 W N K T E L D S F L I E I T A
Zebra Danio Brachydanio rerio NP_998618 511 56508 S258 W N K T E L D S F L I E I T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P41572 481 52473 D228 K W N S A E L D S F L I E I T
Honey Bee Apis mellifera XP_625090 478 52435 D226 D W N K G E L D S F L I E I T
Nematode Worm Caenorhab. elegans Q17761 484 53178 S229 W N K G E L E S F L I E I T A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53319 492 53904 S231 W N T G V L D S F L I E I T R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 94.6 N.A. 94 93.1 N.A. 70.1 89.8 85.7 82.7 N.A. 72.6 73.7 69.6 N.A.
Protein Similarity: 100 N.A. N.A. 98.5 N.A. 97.7 97.9 N.A. 72.3 95 94 87.6 N.A. 84 84.4 83 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 93.3 100 100 N.A. 0 0 86.6 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 93.3 100 100 N.A. 13.3 6.6 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 64 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 77.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 75 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 75 17 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 75 17 9 0 0 0 0 84 17 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 84 17 0 0 0 0 0 % F
% Gly: 0 0 0 17 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 84 17 84 17 0 % I
% Lys: 9 0 67 9 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 84 17 0 0 84 17 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 84 25 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 0 9 0 0 0 84 17 0 0 0 0 0 0 % S
% Thr: 0 0 9 67 0 0 0 0 0 0 0 0 0 84 17 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 84 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _