Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA2 All Species: 13.33
Human Site: S126 Identified Species: 22.56
UniProt: P52292 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52292 NP_002257.1 529 57862 S126 G L I P K F V S F L G R T D C
Chimpanzee Pan troglodytes XP_001170686 399 43075 A18 A W A L T N I A S G T S E Q T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_861990 529 57923 S126 G L I P K F V S F L G R T D C
Cat Felis silvestris
Mouse Mus musculus P52293 529 57910 S126 G L I P K F V S F L G K T D C
Rat Rattus norvegicus Q56R16 536 60281 K131 G V V Q R F V K F L E R N E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509792 529 57894 S126 G M I P K L V S F L G R S D C
Chicken Gallus gallus Q5ZML1 538 60176 E133 G V V A R F V E F L K R K E N
Frog Xenopus laevis P52170 522 57670 E123 G L I P K L V E F L S R H D N
Zebra Danio Brachydanio rerio Q503E9 536 59774 E131 G V V N R F V E F L R R S D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 R119 G I V P I C I R F L Q N T N N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19969 514 56144 V114 S G I L P V L V Q C L S S T D
Sea Urchin Strong. purpuratus XP_788859 520 57200 A118 G L V P K F V A F L G H S D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 E122 G V V P R F V E F L K K E D Y
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 E137 G V V P R L V E F M R E N Q P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.8 N.A. 97.7 N.A. 94.5 48.3 N.A. 87.1 46.2 62.9 48.1 N.A. 50.6 N.A. 44.7 60.8
Protein Similarity: 100 75 N.A. 99.2 N.A. 98.1 65.6 N.A. 95.4 64.1 78.6 66 N.A. 68.2 N.A. 63.3 74.8
P-Site Identity: 100 0 N.A. 100 N.A. 93.3 40 N.A. 80 40 66.6 46.6 N.A. 33.3 N.A. 6.6 66.6
P-Site Similarity: 100 13.3 N.A. 100 N.A. 100 66.6 N.A. 93.3 66.6 66.6 73.3 N.A. 60 N.A. 20 86.6
Percent
Protein Identity: N.A. N.A. N.A. 47.3 43.9 N.A.
Protein Similarity: N.A. N.A. N.A. 64.6 61.4 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 0 0 15 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 29 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 58 8 % D
% Glu: 0 0 0 0 0 0 0 36 0 0 8 8 15 15 0 % E
% Phe: 0 0 0 0 0 58 0 0 86 0 0 0 0 0 0 % F
% Gly: 86 8 0 0 0 0 0 0 0 8 36 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % H
% Ile: 0 8 43 0 8 0 15 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 43 0 0 8 0 0 15 15 8 0 0 % K
% Leu: 0 36 0 15 0 22 8 0 0 79 8 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 0 0 0 0 0 8 15 8 43 % N
% Pro: 0 0 0 65 8 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 8 0 0 0 0 8 0 8 0 0 15 0 % Q
% Arg: 0 0 0 0 36 0 0 8 0 0 15 50 0 0 0 % R
% Ser: 8 0 0 0 0 0 0 29 8 0 8 15 29 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 8 0 29 8 8 % T
% Val: 0 36 50 0 0 8 79 8 0 0 0 0 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _