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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA2 All Species: 19.7
Human Site: S24 Identified Species: 33.33
UniProt: P52292 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.46
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52292 NP_002257.1 529 57862 S24 F K N K G K D S T E M R R R R
Chimpanzee Pan troglodytes XP_001170686 399 43075
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_861990 529 57923 S24 F K N K G K D S T E M R R R R
Cat Felis silvestris
Mouse Mus musculus P52293 529 57910 S24 F K N K G K D S T E M R R R R
Rat Rattus norvegicus Q56R16 536 60281 E42 L R K Q K R E E Q L F K R R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509792 529 57894 S24 F K N K G K D S S E M R R R R
Chicken Gallus gallus Q5ZML1 538 60176 E42 L R K Q K R E E Q L F K R R N
Frog Xenopus laevis P52170 522 57670 S32 R R R R V E V S V E L R K A K
Zebra Danio Brachydanio rerio Q503E9 536 59774 E42 L R K Q K R E E Q L F K R R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 H28 Q D S R M R R H E V T I E L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19969 514 56144 E24 I G K E K R N E E V V S I R K
Sea Urchin Strong. purpuratus XP_788859 520 57200 E28 E L R R R R N E V S V E L R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 E24 K V A V D A E E G R R R R E D
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 S28 F K N K G R F S A D E L R R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.8 N.A. 97.7 N.A. 94.5 48.3 N.A. 87.1 46.2 62.9 48.1 N.A. 50.6 N.A. 44.7 60.8
Protein Similarity: 100 75 N.A. 99.2 N.A. 98.1 65.6 N.A. 95.4 64.1 78.6 66 N.A. 68.2 N.A. 63.3 74.8
P-Site Identity: 100 0 N.A. 100 N.A. 100 13.3 N.A. 93.3 13.3 20 13.3 N.A. 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 0 N.A. 100 N.A. 100 46.6 N.A. 100 46.6 60 46.6 N.A. 26.6 N.A. 40 40
Percent
Protein Identity: N.A. N.A. N.A. 47.3 43.9 N.A.
Protein Similarity: N.A. N.A. N.A. 64.6 61.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 8 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 29 0 0 8 0 0 0 0 8 % D
% Glu: 8 0 0 8 0 8 29 43 15 36 8 8 8 8 0 % E
% Phe: 36 0 0 0 0 0 8 0 0 0 22 0 0 0 0 % F
% Gly: 0 8 0 0 36 0 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % I
% Lys: 8 36 29 36 29 29 0 0 0 0 0 22 8 0 22 % K
% Leu: 22 8 0 0 0 0 0 0 0 22 8 8 8 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 29 0 0 0 0 % M
% Asn: 0 0 36 0 0 0 15 0 0 0 0 0 0 0 22 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 22 0 0 0 0 22 0 0 0 0 0 0 % Q
% Arg: 8 29 15 22 8 50 8 0 0 8 8 43 65 72 43 % R
% Ser: 0 0 8 0 0 0 0 43 8 8 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 22 0 8 0 0 0 0 % T
% Val: 0 8 0 8 8 0 8 0 15 15 15 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _