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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA2
All Species:
40.3
Human Site:
Y495
Identified Species:
68.21
UniProt:
P52292
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52292
NP_002257.1
529
57862
Y495
S
L
S
L
I
E
K
Y
F
S
V
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001170686
399
43075
F366
L
S
L
I
E
K
Y
F
S
V
E
E
E
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_861990
529
57923
Y495
S
L
N
L
I
E
K
Y
F
S
V
E
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P52293
529
57910
Y495
S
L
N
L
I
E
K
Y
F
S
V
E
E
E
E
Rat
Rattus norvegicus
Q56R16
536
60281
Y501
A
F
D
L
I
E
R
Y
F
G
V
E
E
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509792
529
57894
Y495
S
S
S
L
I
E
K
Y
F
S
A
E
E
E
E
Chicken
Gallus gallus
Q5ZML1
538
60176
Y503
A
F
D
L
I
E
H
Y
F
G
T
E
D
E
D
Frog
Xenopus laevis
P52170
522
57670
Y488
A
L
A
L
I
E
K
Y
F
S
G
E
E
A
D
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
Y501
A
F
D
L
I
E
H
Y
F
G
V
E
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
Y485
A
Y
A
I
I
D
T
Y
F
S
N
G
D
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
F477
A
F
E
I
I
D
N
F
F
S
S
D
D
E
T
Sea Urchin
Strong. purpuratus
XP_788859
520
57200
Y483
S
L
E
I
I
E
K
Y
Y
S
P
Q
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
Y493
A
V
K
I
L
E
T
Y
W
L
E
E
E
D
D
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
Y508
A
Y
K
I
I
E
T
Y
F
G
E
E
E
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.8
N.A.
97.7
N.A.
94.5
48.3
N.A.
87.1
46.2
62.9
48.1
N.A.
50.6
N.A.
44.7
60.8
Protein Similarity:
100
75
N.A.
99.2
N.A.
98.1
65.6
N.A.
95.4
64.1
78.6
66
N.A.
68.2
N.A.
63.3
74.8
P-Site Identity:
100
20
N.A.
93.3
N.A.
93.3
53.3
N.A.
86.6
46.6
66.6
60
N.A.
33.3
N.A.
26.6
66.6
P-Site Similarity:
100
46.6
N.A.
100
N.A.
100
80
N.A.
86.6
66.6
86.6
73.3
N.A.
73.3
N.A.
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.3
43.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.6
61.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
15
0
0
0
0
0
0
0
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
22
0
0
15
0
0
0
0
0
8
22
29
43
% D
% Glu:
0
0
15
0
8
79
0
0
0
0
22
79
79
65
43
% E
% Phe:
0
29
0
0
0
0
0
15
79
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
29
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
43
86
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
0
0
8
43
0
0
0
0
0
0
0
0
% K
% Leu:
8
36
8
58
8
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
36
15
15
0
0
0
0
0
8
58
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
22
0
0
0
8
0
0
0
8
% T
% Val:
0
8
0
0
0
0
0
0
0
8
36
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
8
86
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _