Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA1 All Species: 36.67
Human Site: S512 Identified Species: 62.05
UniProt: P52294 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52294 NP_002255.3 538 60249 S512 G T E D E D S S I A P Q V D L
Chimpanzee Pan troglodytes XP_516692 546 61223 S520 G T E D E D S S I A P Q V D L
Rhesus Macaque Macaca mulatta XP_001112502 546 61137 S520 G T E D E D S S I A P Q V D L
Dog Lupus familis XP_857562 494 55356 S468 G T E D E D S S I A P Q V D L
Cat Felis silvestris
Mouse Mus musculus Q60960 538 60164 S512 G T E D E D S S I A P Q V D L
Rat Rattus norvegicus P83953 538 60118 S512 G T E D E D S S I A P Q V D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518163 554 62067 S528 G V E E E D S S I A P Q V D E
Chicken Gallus gallus Q5ZML1 538 60176 S512 G T E D E D S S I A P Q V D L
Frog Xenopus laevis P52170 522 57670 I497 S G E E A D D I A L E P E M G
Zebra Danio Brachydanio rerio Q503E9 536 59774 S510 G V E E E D A S I V P Q V D Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 E494 S N G D D E A E Q E L A P Q E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19969 514 56144 N486 S S D D E T G N V E G A Q S S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 T502 L E E E D D E T Q Q P P G V D
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 D517 G E E E D A V D E T M A P Q N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 98.3 91.2 N.A. 97.7 98.1 N.A. 78.3 95.7 44 80.3 N.A. 44.6 N.A. 42.7 N.A.
Protein Similarity: 100 98.5 98.5 91.6 N.A. 99.4 99.4 N.A. 86.8 98.3 62.2 89 N.A. 61.7 N.A. 61.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 80 100 13.3 66.6 N.A. 6.6 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 100 20 80 N.A. 26.6 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 54.2 48.8 N.A.
Protein Similarity: N.A. N.A. N.A. 69.1 66.6 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 15 0 8 58 0 22 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 65 22 79 8 8 0 0 0 0 0 65 8 % D
% Glu: 0 15 86 36 72 8 8 8 8 15 8 0 8 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 72 8 8 0 0 0 8 0 0 0 8 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 65 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 0 8 8 0 0 0 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 72 15 15 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 15 8 0 65 8 15 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 22 8 0 0 0 0 58 65 0 0 0 0 0 8 8 % S
% Thr: 0 50 0 0 0 8 0 8 0 8 0 0 0 0 0 % T
% Val: 0 15 0 0 0 0 8 0 8 8 0 0 65 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _