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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAP1GDS1 All Species: 18.79
Human Site: S586 Identified Species: 45.93
UniProt: P52306 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52306 NP_001093896.1 607 66317 S586 D V V S K L R S H E N K S V A
Chimpanzee Pan troglodytes XP_001165490 607 66284 S586 D V V S K L R S H E N K S V A
Rhesus Macaque Macaca mulatta XP_001104606 608 66370 S587 D V V S K L R S H E N K S V A
Dog Lupus familis XP_544990 582 63420 S561 D V V S K L R S H E N K S V A
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517876 299 32341 S279 L P T Y G G Q S C R R L L D P
Chicken Gallus gallus
Frog Xenopus laevis O93614 607 66508 S586 D V V S K L R S H E N K T V A
Zebra Danio Brachydanio rerio XP_002667044 453 49074 M433 M L I D T Q G M N E Q L C V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784496 625 67871 L605 L P E T I E T L K R S K E E P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39968 578 63189 N537 D V K N P G S N N N P S S N D
Red Bread Mold Neurospora crassa Q7RXW1 578 62728 N539 D M I R Q I A N R Q I E S D N
Conservation
Percent
Protein Identity: 100 99.5 98.8 93.4 N.A. N.A. N.A. N.A. 41 N.A. 85.5 59.9 N.A. N.A. N.A. N.A. 36.8
Protein Similarity: 100 99.5 99.3 94.2 N.A. N.A. N.A. N.A. 43.8 N.A. 92.9 67.7 N.A. N.A. N.A. N.A. 55.5
P-Site Identity: 100 100 100 100 N.A. N.A. N.A. N.A. 6.6 N.A. 93.3 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. N.A. N.A. N.A. 13.3 N.A. 100 40 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 20.2
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 40.6
P-Site Identity: N.A. N.A. N.A. N.A. 20 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % C
% Asp: 70 0 0 10 0 0 0 0 0 0 0 0 0 20 10 % D
% Glu: 0 0 10 0 0 10 0 0 0 60 0 10 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 20 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 10 10 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 10 0 50 0 0 0 10 0 0 60 0 0 0 % K
% Leu: 20 10 0 0 0 50 0 10 0 0 0 20 10 0 0 % L
% Met: 10 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 20 20 10 50 0 0 10 10 % N
% Pro: 0 20 0 0 10 0 0 0 0 0 10 0 0 0 20 % P
% Gln: 0 0 0 0 10 10 10 0 0 10 10 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 50 0 10 20 10 0 0 0 0 % R
% Ser: 0 0 0 50 0 0 10 60 0 0 10 10 60 0 10 % S
% Thr: 0 0 10 10 10 0 10 0 0 0 0 0 10 0 0 % T
% Val: 0 60 50 0 0 0 0 0 0 0 0 0 0 60 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _