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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKE
All Species:
20
Human Site:
S556
Identified Species:
40
UniProt:
P52429
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52429
NP_003638.1
567
63927
S556
Q
T
D
D
D
I
S
S
T
S
D
Q
E
D
I
Chimpanzee
Pan troglodytes
XP_523803
567
63963
S556
Q
T
D
D
D
I
S
S
T
S
D
Q
E
D
I
Rhesus Macaque
Macaca mulatta
XP_001101454
426
48025
L416
I
G
R
P
V
V
I
L
S
T
R
T
R
A
Y
Dog
Lupus familis
XP_548222
564
63563
S553
Q
T
D
D
D
I
S
S
T
S
D
Q
E
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C6
564
63616
S553
Q
S
D
D
D
I
S
S
P
S
D
H
E
D
V
Rat
Rattus norvegicus
P49621
801
90269
L791
K
T
G
L
F
C
S
L
I
K
R
T
R
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521727
892
99370
V549
Q
S
D
D
D
D
D
V
S
S
A
S
E
P
E
Chicken
Gallus gallus
XP_001234226
571
64140
S556
Q
T
D
D
D
A
S
S
V
S
E
Q
E
H
V
Frog
Xenopus laevis
NP_001087580
552
61220
D535
Q
T
D
D
D
D
D
D
A
S
S
E
S
D
H
Zebra Danio
Brachydanio rerio
NP_001165699
564
63179
S544
Q
T
D
D
D
D
S
S
A
S
E
V
E
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
N785
H
I
L
E
L
S
I
N
F
F
L
F
T
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
A696
E
P
L
G
H
A
A
A
I
I
T
D
V
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
68.6
95.4
N.A.
90.8
27.8
N.A.
51.4
76.8
73.3
69.4
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
100
99.8
71.9
97.5
N.A.
94.8
40.9
N.A.
56.3
85.6
84.1
80.9
N.A.
N.A.
N.A.
41.6
N.A.
P-Site Identity:
100
100
0
100
N.A.
73.3
13.3
N.A.
40
66.6
46.6
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
86.6
26.6
N.A.
53.3
80
53.3
73.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
9
9
17
0
9
0
0
17
9
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
67
67
25
17
9
0
0
34
9
0
50
0
% D
% Glu:
9
0
0
9
0
0
0
0
0
0
17
9
59
0
17
% E
% Phe:
0
0
0
0
9
0
0
0
9
9
0
9
0
0
0
% F
% Gly:
0
9
9
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
9
0
0
0
0
0
0
9
0
9
17
% H
% Ile:
9
9
0
0
0
34
17
0
17
9
0
0
0
0
25
% I
% Lys:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
17
9
9
0
0
17
0
0
9
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% N
% Pro:
0
9
0
9
0
0
0
0
9
0
0
0
0
9
0
% P
% Gln:
67
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
17
0
17
0
9
% R
% Ser:
0
17
0
0
0
9
59
50
17
67
9
9
9
0
0
% S
% Thr:
0
59
0
0
0
0
0
0
25
9
9
17
9
0
0
% T
% Val:
0
0
0
0
9
9
0
9
9
0
0
9
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _