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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKE
All Species:
24.55
Human Site:
Y206
Identified Species:
49.09
UniProt:
P52429
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52429
NP_003638.1
567
63927
Y206
R
K
D
K
K
T
D
Y
E
V
L
A
S
K
L
Chimpanzee
Pan troglodytes
XP_523803
567
63963
Y206
R
K
D
K
K
T
D
Y
E
V
L
A
S
K
L
Rhesus Macaque
Macaca mulatta
XP_001101454
426
48025
V119
M
L
K
N
D
T
K
V
L
D
A
M
P
H
H
Dog
Lupus familis
XP_548222
564
63563
Y203
R
K
D
K
K
T
D
Y
A
V
L
A
S
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1C6
564
63616
Y203
R
K
D
K
N
T
N
Y
E
G
L
A
S
K
F
Rat
Rattus norvegicus
P49621
801
90269
K395
E
R
Q
S
T
A
K
K
E
K
G
S
S
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521727
892
99370
Y199
R
K
G
K
I
T
D
Y
G
K
L
A
S
P
F
Chicken
Gallus gallus
XP_001234226
571
64140
Y206
R
K
D
K
R
T
D
Y
E
K
V
V
P
Y
C
Frog
Xenopus laevis
NP_001087580
552
61220
Y186
K
K
G
K
T
T
D
Y
E
K
L
A
S
S
M
Zebra Danio
Brachydanio rerio
NP_001165699
564
63179
Y195
R
R
R
H
P
D
E
Y
S
K
L
A
A
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
S414
N
F
S
S
H
S
A
S
L
L
Q
A
V
S
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
L348
Y
H
A
L
R
S
K
L
K
Y
E
L
A
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
68.6
95.4
N.A.
90.8
27.8
N.A.
51.4
76.8
73.3
69.4
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
100
99.8
71.9
97.5
N.A.
94.8
40.9
N.A.
56.3
85.6
84.1
80.9
N.A.
N.A.
N.A.
41.6
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
73.3
13.3
N.A.
60
53.3
60
26.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
6.6
93.3
N.A.
80
33.3
N.A.
60
66.6
73.3
46.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
9
0
9
0
9
67
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
42
0
9
9
50
0
0
9
0
0
0
9
0
% D
% Glu:
9
0
0
0
0
0
9
0
50
0
9
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
17
% F
% Gly:
0
0
17
0
0
0
0
0
9
9
9
0
0
0
0
% G
% His:
0
9
0
9
9
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
59
9
59
25
0
25
9
9
42
0
0
0
34
0
% K
% Leu:
0
9
0
9
0
0
0
9
17
9
59
9
0
0
34
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
9
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
17
9
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
9
0
0
9
9
% Q
% Arg:
59
17
9
0
17
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
17
0
17
0
9
9
0
0
9
59
17
0
% S
% Thr:
0
0
0
0
17
67
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
25
9
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
67
0
9
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _