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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2H
All Species:
24.55
Human Site:
S105
Identified Species:
41.54
UniProt:
P52434
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52434
NP_006223.2
150
17143
S105
R
I
E
G
D
E
T
S
T
E
A
A
T
R
L
Chimpanzee
Pan troglodytes
XP_526411
122
13830
S84
P
T
D
D
R
P
S
S
S
A
Y
V
S
Y
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_996451
150
17237
S105
R
I
E
G
D
E
T
S
T
E
A
A
T
R
L
Rat
Rattus norvegicus
XP_226176
151
17092
S106
R
I
E
G
D
E
S
S
T
E
A
A
T
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232695
122
13865
L84
S
T
E
A
A
T
R
L
S
A
Y
V
S
Y
G
Frog
Xenopus laevis
NP_001085470
150
17139
S105
R
I
E
G
D
E
T
S
T
E
A
A
T
R
L
Zebra Danio
Brachydanio rerio
NP_001017600
150
17108
S105
R
I
E
G
D
E
T
S
T
E
A
A
T
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649352
149
17185
H105
R
I
E
G
D
E
A
H
N
E
A
S
R
L
S
Honey Bee
Apis mellifera
XP_394557
151
17160
A105
Y
R
I
E
G
D
E
A
S
N
E
P
S
S
R
Nematode Worm
Caenorhab. elegans
Q19826
148
16993
T105
L
E
D
D
D
T
G
T
D
G
G
K
L
A
A
Sea Urchin
Strong. purpuratus
XP_796332
151
17165
S105
Y
R
I
E
G
D
E
S
L
T
E
A
A
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147399
146
16550
S105
I
S
E
D
T
S
S
S
Q
N
A
K
V
E
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175827
146
16493
T107
I
S
E
R
D
G
K
T
P
K
A
E
L
Y
V
Baker's Yeast
Sacchar. cerevisiae
P20436
146
16493
F104
M
Y
G
T
A
Y
K
F
E
E
V
S
K
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
N.A.
N.A.
N.A.
96.6
91.3
N.A.
N.A.
81.3
97.3
97.3
N.A.
78
77.4
63.3
82.7
Protein Similarity:
100
81.3
N.A.
N.A.
N.A.
98
94.6
N.A.
N.A.
81.3
100
98.6
N.A.
88.6
87.4
80.6
90.7
P-Site Identity:
100
6.6
N.A.
N.A.
N.A.
100
86.6
N.A.
N.A.
6.6
100
100
N.A.
53.3
0
6.6
13.3
P-Site Similarity:
100
33.3
N.A.
N.A.
N.A.
100
93.3
N.A.
N.A.
20
100
100
N.A.
60
26.6
20
20
Percent
Protein Identity:
N.A.
46.6
N.A.
48
36.6
N.A.
Protein Similarity:
N.A.
64.6
N.A.
68.6
58.6
N.A.
P-Site Identity:
N.A.
20
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
15
0
8
8
0
15
58
43
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
15
22
58
15
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
8
65
15
0
43
15
0
8
50
15
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
43
15
8
8
0
0
8
8
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
15
43
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
15
0
0
8
0
15
8
0
8
% K
% Leu:
8
0
0
0
0
0
0
8
8
0
0
0
15
8
43
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
15
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
43
15
0
8
8
0
8
0
0
0
0
0
8
29
8
% R
% Ser:
8
15
0
0
0
8
22
58
22
0
0
15
22
8
8
% S
% Thr:
0
15
0
8
8
15
29
15
36
8
0
0
36
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
15
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
8
0
0
0
8
0
0
0
0
15
0
0
22
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _