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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2H
All Species:
37.88
Human Site:
S32
Identified Species:
64.1
UniProt:
P52434
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52434
NP_006223.2
150
17143
S32
V
S
R
L
H
C
E
S
E
S
F
K
M
D
L
Chimpanzee
Pan troglodytes
XP_526411
122
13830
D11
I
L
F
E
D
I
F
D
V
K
D
I
D
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_996451
150
17237
S32
V
S
R
L
H
C
E
S
E
S
F
K
M
D
L
Rat
Rattus norvegicus
XP_226176
151
17092
S33
V
S
Q
L
H
C
E
S
E
S
F
K
V
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232695
122
13865
D11
I
L
F
E
D
I
F
D
V
K
D
I
D
P
E
Frog
Xenopus laevis
NP_001085470
150
17139
S32
V
S
R
L
H
C
E
S
E
S
F
K
M
D
L
Zebra Danio
Brachydanio rerio
NP_001017600
150
17108
S32
V
S
R
L
H
C
E
S
E
S
F
K
M
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649352
149
17185
S32
V
S
R
L
H
C
E
S
E
S
F
K
M
D
L
Honey Bee
Apis mellifera
XP_394557
151
17160
S32
V
S
R
L
H
C
E
S
E
S
F
K
M
D
L
Nematode Worm
Caenorhab. elegans
Q19826
148
16993
A32
V
S
R
Y
F
C
D
A
E
S
F
K
M
E
L
Sea Urchin
Strong. purpuratus
XP_796332
151
17165
S32
V
S
R
L
H
C
E
S
E
S
F
K
M
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147399
146
16550
S32
V
S
R
V
E
A
R
S
E
Q
L
D
M
Y
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175827
146
16493
S34
V
T
R
V
Q
A
T
S
H
N
L
E
M
F
M
Baker's Yeast
Sacchar. cerevisiae
P20436
146
16493
T31
C
R
I
E
A
A
S
T
T
Q
D
Q
C
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
N.A.
N.A.
N.A.
96.6
91.3
N.A.
N.A.
81.3
97.3
97.3
N.A.
78
77.4
63.3
82.7
Protein Similarity:
100
81.3
N.A.
N.A.
N.A.
98
94.6
N.A.
N.A.
81.3
100
98.6
N.A.
88.6
87.4
80.6
90.7
P-Site Identity:
100
0
N.A.
N.A.
N.A.
100
86.6
N.A.
N.A.
0
100
100
N.A.
100
100
66.6
100
P-Site Similarity:
100
6.6
N.A.
N.A.
N.A.
100
100
N.A.
N.A.
6.6
100
100
N.A.
100
100
86.6
100
Percent
Protein Identity:
N.A.
46.6
N.A.
48
36.6
N.A.
Protein Similarity:
N.A.
64.6
N.A.
68.6
58.6
N.A.
P-Site Identity:
N.A.
40
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
53.3
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
22
0
8
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
65
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
15
0
8
15
0
0
22
8
15
58
0
% D
% Glu:
0
0
0
22
8
0
58
0
72
0
0
8
0
8
15
% E
% Phe:
0
0
15
0
8
0
15
0
0
0
65
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
58
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
15
0
8
0
0
15
0
0
0
0
0
15
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
15
0
65
0
8
0
% K
% Leu:
0
15
0
58
0
0
0
0
0
0
15
0
0
0
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
15
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
15
0
8
0
0
0
% Q
% Arg:
0
8
72
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
72
0
0
0
0
8
72
0
65
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
8
8
8
0
0
0
0
0
0
% T
% Val:
79
0
0
15
0
0
0
0
15
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _