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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2H
All Species:
15.45
Human Site:
T78
Identified Species:
26.15
UniProt:
P52434
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52434
NP_006223.2
150
17143
T78
D
D
G
E
Y
N
P
T
D
D
R
P
S
R
A
Chimpanzee
Pan troglodytes
XP_526411
122
13830
R57
V
D
L
G
D
K
F
R
L
V
I
A
S
T
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_996451
150
17237
T78
D
D
G
E
Y
S
P
T
D
D
R
P
S
R
A
Rat
Rattus norvegicus
XP_226176
151
17092
T79
D
D
G
E
Y
N
P
T
D
G
R
P
S
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232695
122
13865
A57
T
D
D
R
P
S
R
A
D
Q
F
E
Y
V
M
Frog
Xenopus laevis
NP_001085470
150
17139
T78
D
D
G
E
Y
N
P
T
D
D
R
P
S
R
A
Zebra Danio
Brachydanio rerio
NP_001017600
150
17108
Q78
D
D
G
E
Y
N
P
Q
D
D
R
P
S
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649352
149
17185
M78
D
S
G
E
Y
N
P
M
E
H
E
G
T
R
A
Honey Bee
Apis mellifera
XP_394557
151
17160
T78
D
G
G
E
W
N
A
T
E
Q
E
G
G
S
R
Nematode Worm
Caenorhab. elegans
Q19826
148
16993
K78
D
E
G
E
Y
D
P
K
A
E
Y
P
R
I
K
Sea Urchin
Strong. purpuratus
XP_796332
151
17165
L78
D
E
P
D
Y
T
P
L
D
D
G
Q
P
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147399
146
16550
A78
D
T
G
Y
Y
T
Q
A
G
R
K
T
L
A
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175827
146
16493
G80
D
T
G
Y
F
T
P
G
A
K
K
T
L
A
D
Baker's Yeast
Sacchar. cerevisiae
P20436
146
16493
R77
A
N
D
S
S
A
T
R
S
W
R
P
P
Q
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
N.A.
N.A.
N.A.
96.6
91.3
N.A.
N.A.
81.3
97.3
97.3
N.A.
78
77.4
63.3
82.7
Protein Similarity:
100
81.3
N.A.
N.A.
N.A.
98
94.6
N.A.
N.A.
81.3
100
98.6
N.A.
88.6
87.4
80.6
90.7
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
13.3
100
93.3
N.A.
53.3
33.3
40
33.3
P-Site Similarity:
100
13.3
N.A.
N.A.
N.A.
100
93.3
N.A.
N.A.
20
100
93.3
N.A.
66.6
46.6
60
46.6
Percent
Protein Identity:
N.A.
46.6
N.A.
48
36.6
N.A.
Protein Similarity:
N.A.
64.6
N.A.
68.6
58.6
N.A.
P-Site Identity:
N.A.
20
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
15
15
0
0
8
0
15
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
79
50
15
8
8
8
0
0
50
36
0
0
0
0
15
% D
% Glu:
0
15
0
58
0
0
0
0
15
8
15
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
72
8
0
0
0
8
8
8
8
15
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
8
0
8
15
0
0
0
8
% K
% Leu:
0
0
8
0
0
0
0
8
8
0
0
0
15
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
43
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
0
65
0
0
0
0
50
15
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
0
15
0
8
0
8
0
% Q
% Arg:
0
0
0
8
0
0
8
15
0
8
43
0
8
43
15
% R
% Ser:
0
8
0
8
8
15
0
0
8
0
0
0
43
15
0
% S
% Thr:
8
15
0
0
0
22
8
36
0
0
0
15
8
8
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
15
65
0
0
0
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _