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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR2H
All Species:
32.42
Human Site:
Y142
Identified Species:
54.87
UniProt:
P52434
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52434
NP_006223.2
150
17143
Y142
F
E
V
D
S
R
V
Y
L
L
M
K
K
L
A
Chimpanzee
Pan troglodytes
XP_526411
122
13830
L115
E
V
D
S
R
V
Y
L
L
M
K
K
L
A
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_996451
150
17237
Y142
F
E
V
D
S
R
V
Y
L
L
M
K
K
L
V
Rat
Rattus norvegicus
XP_226176
151
17092
Y143
F
E
V
D
S
R
V
Y
L
L
K
K
K
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232695
122
13865
L115
E
V
D
S
R
V
Y
L
L
M
K
K
L
A
F
Frog
Xenopus laevis
NP_001085470
150
17139
Y142
F
E
V
D
S
R
V
Y
L
L
M
K
K
L
A
Zebra Danio
Brachydanio rerio
NP_001017600
150
17108
Y142
F
E
V
D
S
R
V
Y
L
L
M
K
K
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649352
149
17185
Y141
F
E
V
D
Q
H
M
Y
L
L
M
K
R
L
A
Honey Bee
Apis mellifera
XP_394557
151
17160
Y143
F
E
I
D
Q
H
M
Y
L
L
M
K
K
L
A
Nematode Worm
Caenorhab. elegans
Q19826
148
16993
Y140
F
E
V
D
M
N
L
Y
L
L
M
K
K
T
D
Sea Urchin
Strong. purpuratus
XP_796332
151
17165
Y143
V
E
L
N
Q
H
V
Y
L
L
M
K
K
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147399
146
16550
L139
S
F
E
L
D
Q
R
L
F
L
L
I
R
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_175827
146
16493
L139
H
F
E
L
D
Q
R
L
F
L
L
M
R
K
L
Baker's Yeast
Sacchar. cerevisiae
P20436
146
16493
Q137
R
N
L
N
N
L
K
Q
E
N
A
Y
L
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.3
N.A.
N.A.
N.A.
96.6
91.3
N.A.
N.A.
81.3
97.3
97.3
N.A.
78
77.4
63.3
82.7
Protein Similarity:
100
81.3
N.A.
N.A.
N.A.
98
94.6
N.A.
N.A.
81.3
100
98.6
N.A.
88.6
87.4
80.6
90.7
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
13.3
100
100
N.A.
73.3
73.3
66.6
66.6
P-Site Similarity:
100
20
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
20
100
100
N.A.
86.6
86.6
73.3
80
Percent
Protein Identity:
N.A.
46.6
N.A.
48
36.6
N.A.
Protein Similarity:
N.A.
64.6
N.A.
68.6
58.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
15
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
58
15
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
15
65
15
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
58
15
0
0
0
0
0
0
15
0
0
0
0
0
15
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
22
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
22
79
58
15
0
% K
% Leu:
0
0
15
15
0
8
8
29
79
79
15
0
22
65
8
% L
% Met:
0
0
0
0
8
0
15
0
0
15
58
8
0
0
0
% M
% Asn:
0
8
0
15
8
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
22
15
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
15
36
15
0
0
0
0
0
22
0
0
% R
% Ser:
8
0
0
15
36
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
8
15
50
0
0
15
43
0
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
65
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _